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An elaborate sweep-stick code in rat barrel cortex
In rat barrel cortex, feature encoding schemes uncovered during broadband whisker stimulation are hard to reconcile with the simple stick-slip code observed during natural tactile behaviors, and this has hindered the development of a generalized computational framework. By designing broadband artifi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494352/ https://www.ncbi.nlm.nih.gov/pubmed/32938665 http://dx.doi.org/10.1126/sciadv.abb7189 |
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author | Harrell, Evan R. Goldin, Matías A. Bathellier, Brice Shulz, Daniel E. |
author_facet | Harrell, Evan R. Goldin, Matías A. Bathellier, Brice Shulz, Daniel E. |
author_sort | Harrell, Evan R. |
collection | PubMed |
description | In rat barrel cortex, feature encoding schemes uncovered during broadband whisker stimulation are hard to reconcile with the simple stick-slip code observed during natural tactile behaviors, and this has hindered the development of a generalized computational framework. By designing broadband artificial stimuli to sample the inputs encoded under natural conditions, we resolve this disparity while markedly increasing the percentage of deep layer neurons found to encode whisker movements, as well as the diversity of these encoded features. Deep layer neurons encode two main types of events, sticks and sweeps, corresponding to high angular velocity bumps and large angular displacements with high velocity, respectively. Neurons can exclusively encode sticks or sweeps, or they can encode both, with or without direction selectivity. Beyond unifying coding theories from naturalistic and artificial stimulation studies, these findings delineate a simple and generalizable set of whisker movement features that can support a range of perceptual processes. |
format | Online Article Text |
id | pubmed-7494352 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | American Association for the Advancement of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-74943522020-09-23 An elaborate sweep-stick code in rat barrel cortex Harrell, Evan R. Goldin, Matías A. Bathellier, Brice Shulz, Daniel E. Sci Adv Research Articles In rat barrel cortex, feature encoding schemes uncovered during broadband whisker stimulation are hard to reconcile with the simple stick-slip code observed during natural tactile behaviors, and this has hindered the development of a generalized computational framework. By designing broadband artificial stimuli to sample the inputs encoded under natural conditions, we resolve this disparity while markedly increasing the percentage of deep layer neurons found to encode whisker movements, as well as the diversity of these encoded features. Deep layer neurons encode two main types of events, sticks and sweeps, corresponding to high angular velocity bumps and large angular displacements with high velocity, respectively. Neurons can exclusively encode sticks or sweeps, or they can encode both, with or without direction selectivity. Beyond unifying coding theories from naturalistic and artificial stimulation studies, these findings delineate a simple and generalizable set of whisker movement features that can support a range of perceptual processes. American Association for the Advancement of Science 2020-09-16 /pmc/articles/PMC7494352/ /pubmed/32938665 http://dx.doi.org/10.1126/sciadv.abb7189 Text en Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (https://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited. |
spellingShingle | Research Articles Harrell, Evan R. Goldin, Matías A. Bathellier, Brice Shulz, Daniel E. An elaborate sweep-stick code in rat barrel cortex |
title | An elaborate sweep-stick code in rat barrel cortex |
title_full | An elaborate sweep-stick code in rat barrel cortex |
title_fullStr | An elaborate sweep-stick code in rat barrel cortex |
title_full_unstemmed | An elaborate sweep-stick code in rat barrel cortex |
title_short | An elaborate sweep-stick code in rat barrel cortex |
title_sort | elaborate sweep-stick code in rat barrel cortex |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494352/ https://www.ncbi.nlm.nih.gov/pubmed/32938665 http://dx.doi.org/10.1126/sciadv.abb7189 |
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