Annexin A1–dependent tethering promotes extracellular vesicle aggregation revealed with single–extracellular vesicle analysis

Extracellular vesicles (EVs) including plasma membrane–derived microvesicles and endosomal-derived exosomes aggregate by unknown mechanisms, forming microcalcifications that promote cardiovascular disease, the leading cause of death worldwide. Here, we show a framework for assessing cell-independent...

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Detalles Bibliográficos
Autores principales: Rogers, Maximillian A., Buffolo, Fabrizio, Schlotter, Florian, Atkins, Samantha K., Lee, Lang H., Halu, Arda, Blaser, Mark C., Tsolaki, Elena, Higashi, Hideyuki, Luther, Kristin, Daaboul, George, Bouten, Carlijn V.C., Body, Simon C., Singh, Sasha A., Bertazzo, Sergio, Libby, Peter, Aikawa, Masanori, Aikawa, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494353/
https://www.ncbi.nlm.nih.gov/pubmed/32938681
http://dx.doi.org/10.1126/sciadv.abb1244

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