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PEG-Ceramide Nanomicelles Induce Autophagy and Degrade Tau Proteins in N2a Cells
PURPOSE: Alzheimer’s disease (AD) is a neurodegenerative disorder that manifests as abnormal behavior and a progressive decline in memory. Although the pathogenesis of AD is due to the excessive deposition of amyloid β protein (Aβ) outside the neurons in the brain, evidence suggests that tau protein...
Autores principales: | Gao, Jie, Chen, Xiaohan, Ma, Tianjun, He, Bin, Li, Peng, Zhao, Yucheng, Ma, Yuejin, Zhuang, Jianhua, Yin, You |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494393/ https://www.ncbi.nlm.nih.gov/pubmed/32982233 http://dx.doi.org/10.2147/IJN.S258311 |
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