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CircRNAs: A New Chapter in Oral Squamous Cell Carcinoma Biology

With the rapid development of bioinformatics and gene sequencing technologies, understanding of circular RNAs (circRNAs) has been extended, and numerous studies have identified the key regulator role of circRNAs in a variety of diseases, especially in cancer. Recently, accumulated studies of oral sq...

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Detalles Bibliográficos
Autores principales: Fan, Hua-yang, Jiang, Jian, Tang, Ya-jie, Liang, Xin-hua, Tang, Ya-ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494394/
https://www.ncbi.nlm.nih.gov/pubmed/32982296
http://dx.doi.org/10.2147/OTT.S263655
Descripción
Sumario:With the rapid development of bioinformatics and gene sequencing technologies, understanding of circular RNAs (circRNAs) has been extended, and numerous studies have identified the key regulator role of circRNAs in a variety of diseases, especially in cancer. Recently, accumulated studies of oral squamous cell carcinoma (OSCC) have discovered the great potential of circRNAs, which can serve as prognostic or diagnostic biomarkers and affect the development and therapy of OSCC. In this review, we detail the new progress of circRNA research for OSCC in order to provide new strategies for clinical diagnosis and treatment.