First case of IMP-15-producing Pseudomonas aeruginosa in Switzerland: Challenging laboratory diagnosis using whole genome sequencing (WGS)

We report on the first case of multiresistant Pseudomonas aeruginosa harbouring the metallo-β-lactamase IMP-15 isolated in Switzerland from a patient repatriated from Cambodia. The laboratory diagnosis of IMP-15 was hampered by two negative tests for carbapenemase detection. The carbapenemase gene w...

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Detalles Bibliográficos
Autores principales: Goldenberger, Daniel, Vuichard-Gysin, Danielle, Herzog, Kathrin, Hinić, Vladimira, Seth-Smith, Helena, Egli, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494785/
https://www.ncbi.nlm.nih.gov/pubmed/32983889
http://dx.doi.org/10.1016/j.idcr.2020.e00933
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author Goldenberger, Daniel
Vuichard-Gysin, Danielle
Herzog, Kathrin
Hinić, Vladimira
Seth-Smith, Helena
Egli, Adrian
author_facet Goldenberger, Daniel
Vuichard-Gysin, Danielle
Herzog, Kathrin
Hinić, Vladimira
Seth-Smith, Helena
Egli, Adrian
author_sort Goldenberger, Daniel
collection PubMed
description We report on the first case of multiresistant Pseudomonas aeruginosa harbouring the metallo-β-lactamase IMP-15 isolated in Switzerland from a patient repatriated from Cambodia. The laboratory diagnosis of IMP-15 was hampered by two negative tests for carbapenemase detection. The carbapenemase gene was subsequently detected by whole genome sequencing and the isolate further characterised by various phenotypic and genotypic analyses.
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spelling pubmed-74947852020-09-24 First case of IMP-15-producing Pseudomonas aeruginosa in Switzerland: Challenging laboratory diagnosis using whole genome sequencing (WGS) Goldenberger, Daniel Vuichard-Gysin, Danielle Herzog, Kathrin Hinić, Vladimira Seth-Smith, Helena Egli, Adrian IDCases Article We report on the first case of multiresistant Pseudomonas aeruginosa harbouring the metallo-β-lactamase IMP-15 isolated in Switzerland from a patient repatriated from Cambodia. The laboratory diagnosis of IMP-15 was hampered by two negative tests for carbapenemase detection. The carbapenemase gene was subsequently detected by whole genome sequencing and the isolate further characterised by various phenotypic and genotypic analyses. Elsevier 2020-09-02 /pmc/articles/PMC7494785/ /pubmed/32983889 http://dx.doi.org/10.1016/j.idcr.2020.e00933 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Goldenberger, Daniel
Vuichard-Gysin, Danielle
Herzog, Kathrin
Hinić, Vladimira
Seth-Smith, Helena
Egli, Adrian
First case of IMP-15-producing Pseudomonas aeruginosa in Switzerland: Challenging laboratory diagnosis using whole genome sequencing (WGS)
title First case of IMP-15-producing Pseudomonas aeruginosa in Switzerland: Challenging laboratory diagnosis using whole genome sequencing (WGS)
title_full First case of IMP-15-producing Pseudomonas aeruginosa in Switzerland: Challenging laboratory diagnosis using whole genome sequencing (WGS)
title_fullStr First case of IMP-15-producing Pseudomonas aeruginosa in Switzerland: Challenging laboratory diagnosis using whole genome sequencing (WGS)
title_full_unstemmed First case of IMP-15-producing Pseudomonas aeruginosa in Switzerland: Challenging laboratory diagnosis using whole genome sequencing (WGS)
title_short First case of IMP-15-producing Pseudomonas aeruginosa in Switzerland: Challenging laboratory diagnosis using whole genome sequencing (WGS)
title_sort first case of imp-15-producing pseudomonas aeruginosa in switzerland: challenging laboratory diagnosis using whole genome sequencing (wgs)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494785/
https://www.ncbi.nlm.nih.gov/pubmed/32983889
http://dx.doi.org/10.1016/j.idcr.2020.e00933
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