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Ancient foe, serious weapon: Subarachnoid hemorrhage secondary to TB meningitis

Tuberculosis is an ancient infectious disease with global distribution and a multitude of multisystem presentations. Infection of the central nervous system (CNS) is the most serious presentation manifested as tuberculous meningitis (TBM), intracranial tuberculoma, and tuberculous arachnoiditis all...

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Autores principales: Ali, Mohammed Omer khalil, Elhassan, Ahmed E., Elgara, Mohamed S., Abdelhady, Mohamed, Abdel Hadi, Hamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494791/
https://www.ncbi.nlm.nih.gov/pubmed/32983890
http://dx.doi.org/10.1016/j.idcr.2020.e00941
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author Ali, Mohammed Omer khalil
Elhassan, Ahmed E.
Elgara, Mohamed S.
Abdelhady, Mohamed
Abdel Hadi, Hamad
author_facet Ali, Mohammed Omer khalil
Elhassan, Ahmed E.
Elgara, Mohamed S.
Abdelhady, Mohamed
Abdel Hadi, Hamad
author_sort Ali, Mohammed Omer khalil
collection PubMed
description Tuberculosis is an ancient infectious disease with global distribution and a multitude of multisystem presentations. Infection of the central nervous system (CNS) is the most serious presentation manifested as tuberculous meningitis (TBM), intracranial tuberculoma, and tuberculous arachnoiditis all associated with significant morbidity and mortality. TBM is the commonest form of CNS manifestations capable of causing secondary arteritis leading to vascular complications. We report a case of a 22-year-old Indian patient diagnosed with TBM who subsequently presented with sudden onset severe headache, which was eventually diagnosed as subarachnoid hemorrhage. Radiological assessment confirmed secondary complications with cerebral aneurysmal dilatation attributed to TBM. The patient was safely managed with combined radiological and surgical interventions with uneventful outcomes. Review of the literature revealed that such complication of TBM is rare usually with serious implications. We aim to highlight to infection specialists to be aware of such association.
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spelling pubmed-74947912020-09-24 Ancient foe, serious weapon: Subarachnoid hemorrhage secondary to TB meningitis Ali, Mohammed Omer khalil Elhassan, Ahmed E. Elgara, Mohamed S. Abdelhady, Mohamed Abdel Hadi, Hamad IDCases Case Report Tuberculosis is an ancient infectious disease with global distribution and a multitude of multisystem presentations. Infection of the central nervous system (CNS) is the most serious presentation manifested as tuberculous meningitis (TBM), intracranial tuberculoma, and tuberculous arachnoiditis all associated with significant morbidity and mortality. TBM is the commonest form of CNS manifestations capable of causing secondary arteritis leading to vascular complications. We report a case of a 22-year-old Indian patient diagnosed with TBM who subsequently presented with sudden onset severe headache, which was eventually diagnosed as subarachnoid hemorrhage. Radiological assessment confirmed secondary complications with cerebral aneurysmal dilatation attributed to TBM. The patient was safely managed with combined radiological and surgical interventions with uneventful outcomes. Review of the literature revealed that such complication of TBM is rare usually with serious implications. We aim to highlight to infection specialists to be aware of such association. Elsevier 2020-09-08 /pmc/articles/PMC7494791/ /pubmed/32983890 http://dx.doi.org/10.1016/j.idcr.2020.e00941 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ali, Mohammed Omer khalil
Elhassan, Ahmed E.
Elgara, Mohamed S.
Abdelhady, Mohamed
Abdel Hadi, Hamad
Ancient foe, serious weapon: Subarachnoid hemorrhage secondary to TB meningitis
title Ancient foe, serious weapon: Subarachnoid hemorrhage secondary to TB meningitis
title_full Ancient foe, serious weapon: Subarachnoid hemorrhage secondary to TB meningitis
title_fullStr Ancient foe, serious weapon: Subarachnoid hemorrhage secondary to TB meningitis
title_full_unstemmed Ancient foe, serious weapon: Subarachnoid hemorrhage secondary to TB meningitis
title_short Ancient foe, serious weapon: Subarachnoid hemorrhage secondary to TB meningitis
title_sort ancient foe, serious weapon: subarachnoid hemorrhage secondary to tb meningitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494791/
https://www.ncbi.nlm.nih.gov/pubmed/32983890
http://dx.doi.org/10.1016/j.idcr.2020.e00941
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