BCAT1 binds the RNA-binding protein ZNF423 to activate autophagy via the IRE1-XBP-1-RIDD axis in hypoxic PASMCs

Abnormal functional changes in pulmonary artery smooth muscle cells are the main causes of many lung diseases. Among, autophagy plays a crucial role. However, the specific molecular regulatory mechanism of autophagy in PASMCs remains unclear. Here, we first demonstrate that BCAT1 played a key role i...

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Detalles Bibliográficos
Autores principales: Xin, Wei, Zhang, Min, Yu, Yang, Li, Songlin, Ma, Cui, Zhang, Junting, Jiang, Yuan, Li, Yiying, Zheng, Xiaodong, Zhang, Lixin, Zhao, Xijuan, Pei, Xuzhong, Zhu, Daling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494854/
https://www.ncbi.nlm.nih.gov/pubmed/32938905
http://dx.doi.org/10.1038/s41419-020-02930-y

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