Intercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart

Intercalated discs (ICD), specific cell-to-cell contacts that connect adjacent cardiomyocytes, ensure mechanical and electrochemical coupling during contraction of the heart. Mutations in genes encoding ICD components are linked to cardiovascular diseases. Here, we show that loss of Xinβ, a newly-id...

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Detalles Bibliográficos
Autores principales: Guo, Haipeng, Lu, Yao Wei, Lin, Zhiqiang, Huang, Zhan-Peng, Liu, Jianming, Wang, Yi, Seok, Hee Young, Hu, Xiaoyun, Ma, Qing, Li, Kathryn, Kyselovic, Jan, Wang, Qingchuan, Lin, Jenny L.-C., Lin, Jim J.-C., Cowan, Douglas B., Naya, Francisco, Chen, Yuguo, Pu, William T., Wang, Da-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494909/
https://www.ncbi.nlm.nih.gov/pubmed/32938943
http://dx.doi.org/10.1038/s41467-020-18379-8

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