Hemoglobin stimulates vigorous growth of Streptococcus pneumoniae and shapes the pathogen's global transcriptome

Streptococcus pneumoniae (Spn) must acquire iron from the host to establish infection. We examined the impact of hemoglobin, the largest iron reservoir in the body, on pneumococcal physiology. Supplementation with hemoglobin allowed Spn to resume growth in an iron-deplete medium. Pneumococcal growth...

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Detalles Bibliográficos
Autores principales: Akhter, Fahmina, Womack, Edroyal, Vidal, Jorge E., Le Breton, Yoann, McIver, Kevin S., Pawar, Shrikant, Eichenbaum, Zehava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494912/
https://www.ncbi.nlm.nih.gov/pubmed/32938947
http://dx.doi.org/10.1038/s41598-020-71910-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494912/
https://www.ncbi.nlm.nih.gov/pubmed/32938947
http://dx.doi.org/10.1038/s41598-020-71910-1

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