Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy

Intratumor spatial heterogeneity facilitates therapeutic resistance in glioblastoma (GBM). Nonetheless, understanding of GBM heterogeneity is largely limited to the surgically resectable tumor core lesion while the seeds for recurrence reside in the unresectable tumor edge. In this study, stratifica...

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Detalles Bibliográficos
Autores principales: Bastola, Soniya, Pavlyukov, Marat S., Yamashita, Daisuke, Ghosh, Sadashib, Cho, Heejin, Kagaya, Noritaka, Zhang, Zhuo, Minata, Mutsuko, Lee, Yeri, Sadahiro, Hirokazu, Yamaguchi, Shinobu, Komarova, Svetlana, Yang, Eddy, Markert, James, Nabors, Louis B., Bhat, Krishna, Lee, James, Chen, Qin, Crossman, David K., Shin-Ya, Kazuo, Nam, Do-Hyun, Nakano, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494913/
https://www.ncbi.nlm.nih.gov/pubmed/32938908
http://dx.doi.org/10.1038/s41467-020-18189-y

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