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A membrane transporter determines the spectrum of activity of a potent platinum–acridine hybrid anticancer agent
Cytotoxic drugs that are mechanistically distinct from current chemotherapies are attractive components of personalized combination regimens for combatting aggressive forms of cancer. To gain insight into the cellular mechanism of a potent platinum–acridine anticancer agent (compound 1), a correlati...
Autores principales: | Yao, Xiyuan, Watkins, Noah H., Brown-Harding, Heather, Bierbach, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494928/ https://www.ncbi.nlm.nih.gov/pubmed/32939009 http://dx.doi.org/10.1038/s41598-020-72099-z |
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