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The Framingham Heart Study: Populational CT-based phenotyping in the lungs and mediastinum

The Framingham Heart Study (FHS) is one of the largest and established longitudinal populational cohorts. CT cohorts of the FHS since 2002 provided a unique opportunity to assess non-cardiac thoracic imaging findings. This review deals with image-based phenotyping studies from recent major publicati...

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Detalles Bibliográficos
Autores principales: Araki, Tetsuro, Washko, George R., Schiebler, Mark L., O’Connor, George T., Hatabu, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495061/
https://www.ncbi.nlm.nih.gov/pubmed/32984450
http://dx.doi.org/10.1016/j.ejro.2020.100260
Descripción
Sumario:The Framingham Heart Study (FHS) is one of the largest and established longitudinal populational cohorts. CT cohorts of the FHS since 2002 provided a unique opportunity to assess non-cardiac thoracic imaging findings. This review deals with image-based phenotyping studies from recent major publications regarding interstitial lung abnormalities (ILAs), pulmonary cysts, emphysema, pulmonary nodules, pleural plaques, normal spectrum of the thymus, and anterior mediastinal masses, concluding with the discussion of future directions of FHS CT cohorts studies in the era of radiomics and artificial intelligence.