Cargando…
The Emerging Therapeutic Potential of Nitro Fatty Acids and Other Michael Acceptor-Containing Drugs for the Treatment of Inflammation and Cancer
Nitro fatty acids (NFAs) are endogenously generated lipid mediators deriving from reactions of unsaturated electrophilic fatty acids with reactive nitrogen species. Furthermore, Mediterranean diets can be a source of NFA. These highly electrophilic fatty acids can undergo Michael addition reaction w...
Autores principales: | Piesche, Matthias, Roos, Jessica, Kühn, Benjamin, Fettel, Jasmin, Hellmuth, Nadine, Brat, Camilla, Maucher, Isabelle V., Awad, Omar, Matrone, Carmela, Comerma Steffensen, Simon Gabriel, Manolikakes, Georg, Heinicke, Ulrike, Zacharowski, Kai D., Steinhilber, Dieter, Maier, Thorsten J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495092/ https://www.ncbi.nlm.nih.gov/pubmed/33013366 http://dx.doi.org/10.3389/fphar.2020.01297 |
Ejemplares similares
-
Structural Modifications Yield Novel Insights Into the Intriguing Pharmacodynamic Potential of Anti-inflammatory Nitro-Fatty Acids
por: Hellmuth, Nadine, et al.
Publicado: (2021) -
Cu-catalyzed carboboration of acetylene with Michael acceptors
por: Cheng, Tairan, et al.
Publicado: (2022) -
Nucleophilicity of Glutathione: A Link to Michael Acceptor Reactivities
por: Mayer, Robert J., et al.
Publicado: (2019) -
Trifluoromethylcinnamanilide Michael Acceptors for Treatment of Resistant Bacterial Infections
por: Strharsky, Tomas, et al.
Publicado: (2022) -
Michael acceptor molecules in natural products and their mechanism of action
por: Liang, Song-Ting, et al.
Publicado: (2022)