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Adipocyte Reprogramming by the Transcriptional Coregulator GPS2 Impacts Beta Cell Insulin Secretion
Glucose homeostasis is maintained through organ crosstalk that regulates secretion of insulin to keep blood glucose levels within a physiological range. In type 2 diabetes, this coordinated response is altered, leading to a deregulation of beta cell function and inadequate insulin secretion. Reprogr...
Autores principales: | Drareni, Karima, Ballaire, Raphaëlle, Alzaid, Fawaz, Goncalves, Andreia, Chollet, Catherine, Barilla, Serena, Nguewa, Jean-Louis, Dias, Karine, Lemoine, Sophie, Riveline, Jean-Pierre, Roussel, Ronan, Dalmas, Elise, Velho, Gilberto, Treuter, Eckardt, Gautier, Jean-François, Venteclef, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495095/ https://www.ncbi.nlm.nih.gov/pubmed/32937117 http://dx.doi.org/10.1016/j.celrep.2020.108141 |
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