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Assessment of Placebo Response in Objective and Subjective Outcome Measures in Rheumatoid Arthritis Clinical Trials

IMPORTANCE: Large placebo responses in randomized clinical trials may keep effective medication from reaching the market. Primary outcome measures of clinical trials have shifted from patient-reported to objective outcomes, partly because response to randomized placebo treatment is thought to be gre...

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Detalles Bibliográficos
Autores principales: Vollert, Jan, Cook, Nancy R., Kaptchuk, Ted J., Sehra, Shiv T., Tobias, Deirdre K., Hall, Kathryn T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495232/
https://www.ncbi.nlm.nih.gov/pubmed/32936297
http://dx.doi.org/10.1001/jamanetworkopen.2020.13196