The effect of food and formulation on the population pharmacokinetics of cholesteryl ester transferase protein inhibitor DRL‐17822 in healthy male volunteers

We aimed to characterise the population pharmacokinetics of cholesteryl ester transferase protein inhibitor DRL‐17822 in healthy males and explore the effect of food and formulation on the oral absorption of DRL‐17822 in 4 phase I studies. DRL‐17822 was dosed orally (2–1000 mg) in 2 different drug f...

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Detalles Bibliográficos
Autores principales: Goulooze, Sebastiaan C., Kruithof, Annelieke C., Alikunju, Shanavas, Gautam, Anirudh, Burggraaf, Jacobus, Kamerling, Ingrid M.C., Stevens, Jasper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495284/
https://www.ncbi.nlm.nih.gov/pubmed/32250455
http://dx.doi.org/10.1111/bcp.14297

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