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Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans

The human betacoronaviruses HKU1 and OC43 (subgenus Embecovirus) arose from separate zoonotic introductions, OC43 relatively recently and HKU1 apparently much longer ago. Embecovirus particles contain two surface projections called spike (S) and haemagglutinin-esterase (HE), with S mediating recepto...

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Detalles Bibliográficos
Autores principales:	Hurdiss, Daniel L., Drulyte, Ieva, Lang, Yifei, Shamorkina, Tatiana M., Pronker, Matti F., van Kuppeveld, Frank J. M., Snijder, Joost, de Groot, Raoul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495468/ https://www.ncbi.nlm.nih.gov/pubmed/32938911 http://dx.doi.org/10.1038/s41467-020-18440-6

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