IMPROvER: the Integral Membrane Protein Stability Selector

Identifying stabilising variants of membrane protein targets is often required for structure determination. Our new computational pipeline, the Integral Membrane Protein Stability Selector (IMPROvER) provides a rational approach to variant selection by employing three independent approaches: deep-se...

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Detalles Bibliográficos
Autores principales: Harborne, Steven P. D., Strauss, Jannik, Boakes, Jessica C., Wright, Danielle L., Henderson, James G., Boivineau, Jacques, Jaakola, Veli-Pekka, Goldman, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495477/
https://www.ncbi.nlm.nih.gov/pubmed/32938971
http://dx.doi.org/10.1038/s41598-020-71744-x

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