Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy

Ibrutinib is approved for chronic lymphocytic leukemia (CLL). However, its role in the treatment of multiple myeloma (MM) is not clear and is under investigation. We report a case of CLL that developed MM while on therapy with ibrutinib indicating that this drug may not be active against MM.

Detalles Bibliográficos
Autores principales: Al‐Katib, Ayad M., Gaith, Hussein, Sano, Dahlia, Al‐Katib, Sayf, Bonnett, Michelle, Kafri, Zyad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495781/
https://www.ncbi.nlm.nih.gov/pubmed/32983498
http://dx.doi.org/10.1002/ccr3.3019
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author Al‐Katib, Ayad M.
Gaith, Hussein
Sano, Dahlia
Al‐Katib, Sayf
Bonnett, Michelle
Kafri, Zyad
author_facet Al‐Katib, Ayad M.
Gaith, Hussein
Sano, Dahlia
Al‐Katib, Sayf
Bonnett, Michelle
Kafri, Zyad
author_sort Al‐Katib, Ayad M.
collection PubMed
description Ibrutinib is approved for chronic lymphocytic leukemia (CLL). However, its role in the treatment of multiple myeloma (MM) is not clear and is under investigation. We report a case of CLL that developed MM while on therapy with ibrutinib indicating that this drug may not be active against MM.
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spelling pubmed-74957812020-09-25 Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy Al‐Katib, Ayad M. Gaith, Hussein Sano, Dahlia Al‐Katib, Sayf Bonnett, Michelle Kafri, Zyad Clin Case Rep Case Reports Ibrutinib is approved for chronic lymphocytic leukemia (CLL). However, its role in the treatment of multiple myeloma (MM) is not clear and is under investigation. We report a case of CLL that developed MM while on therapy with ibrutinib indicating that this drug may not be active against MM. John Wiley and Sons Inc. 2020-07-15 /pmc/articles/PMC7495781/ /pubmed/32983498 http://dx.doi.org/10.1002/ccr3.3019 Text en © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Al‐Katib, Ayad M.
Gaith, Hussein
Sano, Dahlia
Al‐Katib, Sayf
Bonnett, Michelle
Kafri, Zyad
Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy
title Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy
title_full Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy
title_fullStr Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy
title_full_unstemmed Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy
title_short Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy
title_sort emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495781/
https://www.ncbi.nlm.nih.gov/pubmed/32983498
http://dx.doi.org/10.1002/ccr3.3019
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