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Morphological features of anterior segment: factors influencing intraocular pressure after cataract surgery in nanophthalmos

PURPOSE: To investigate the anterior segment in nanophthalmic eyes and their association with intraocular pressure after cataract surgery. METHODS: Thirty-two nanophthalmic eyes (axial length [AL] < 18.5 mm) in 18 patients and 35 normal eyes (21 ≤ AL ≤ 24.5 mm) in 35 controls who had undergone un...

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Detalles Bibliográficos
Autores principales: Lu, Qiang, He, Wenwen, Lu, Yi, Zhu, Xiangjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495875/
https://www.ncbi.nlm.nih.gov/pubmed/32974413
http://dx.doi.org/10.1186/s40662-020-00212-4
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author Lu, Qiang
He, Wenwen
Lu, Yi
Zhu, Xiangjia
author_facet Lu, Qiang
He, Wenwen
Lu, Yi
Zhu, Xiangjia
author_sort Lu, Qiang
collection PubMed
description PURPOSE: To investigate the anterior segment in nanophthalmic eyes and their association with intraocular pressure after cataract surgery. METHODS: Thirty-two nanophthalmic eyes (axial length [AL] < 18.5 mm) in 18 patients and 35 normal eyes (21 ≤ AL ≤ 24.5 mm) in 35 controls who had undergone uneventful cataract surgery were included. Swept-source optical coherence tomography was used to compare the anterior segment structures between the two groups. The associations between the anterior segment characteristics of nanophthalmic eyes and postoperative intraocular pressure (IOP) were also investigated. RESULTS: The IOP-lowering effect of cataract surgery was remarkably insufficient in nanophthalmic eyes. Peripheral anterior synechiae (PAS) were observed in 56% (18/32) of nanophthalmic eyes, and a characteristic boomerang-shaped iris was observed in 28% (9/32). The anterior surface of the iris seemed “smoother” in nanophthalmic eyes than in normal eyes. Schlemm’s canal (SC) diameter, SC area, trabecular meshwork (TM) thickness, TM width, and TM area were generally smaller in the nanophthalmic eyes. Younger age, higher preoperative IOP, broader PAS, and smaller SC area were main contributors to higher postoperative IOP. AL and SC diameter may also be of great importance in IOP prediction in patients without glaucoma surgery and PAS. CONCLUSIONS: The morphological features of the anterior segment in nanophthalmic eyes are significantly different from those of normal eyes. Influencing factors such as age, AL, preoperative IOP, extent of PAS, SC and TM size could all be prognostic for IOP after cataract surgery in nanophthalmic eyes. TRIAL REGISTRATION: ClinicalTrails.gov, Trial registration number: NCT02182921, Registered 8 July 2014.
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spelling pubmed-74958752020-09-23 Morphological features of anterior segment: factors influencing intraocular pressure after cataract surgery in nanophthalmos Lu, Qiang He, Wenwen Lu, Yi Zhu, Xiangjia Eye Vis (Lond) Research PURPOSE: To investigate the anterior segment in nanophthalmic eyes and their association with intraocular pressure after cataract surgery. METHODS: Thirty-two nanophthalmic eyes (axial length [AL] < 18.5 mm) in 18 patients and 35 normal eyes (21 ≤ AL ≤ 24.5 mm) in 35 controls who had undergone uneventful cataract surgery were included. Swept-source optical coherence tomography was used to compare the anterior segment structures between the two groups. The associations between the anterior segment characteristics of nanophthalmic eyes and postoperative intraocular pressure (IOP) were also investigated. RESULTS: The IOP-lowering effect of cataract surgery was remarkably insufficient in nanophthalmic eyes. Peripheral anterior synechiae (PAS) were observed in 56% (18/32) of nanophthalmic eyes, and a characteristic boomerang-shaped iris was observed in 28% (9/32). The anterior surface of the iris seemed “smoother” in nanophthalmic eyes than in normal eyes. Schlemm’s canal (SC) diameter, SC area, trabecular meshwork (TM) thickness, TM width, and TM area were generally smaller in the nanophthalmic eyes. Younger age, higher preoperative IOP, broader PAS, and smaller SC area were main contributors to higher postoperative IOP. AL and SC diameter may also be of great importance in IOP prediction in patients without glaucoma surgery and PAS. CONCLUSIONS: The morphological features of the anterior segment in nanophthalmic eyes are significantly different from those of normal eyes. Influencing factors such as age, AL, preoperative IOP, extent of PAS, SC and TM size could all be prognostic for IOP after cataract surgery in nanophthalmic eyes. TRIAL REGISTRATION: ClinicalTrails.gov, Trial registration number: NCT02182921, Registered 8 July 2014. BioMed Central 2020-09-09 /pmc/articles/PMC7495875/ /pubmed/32974413 http://dx.doi.org/10.1186/s40662-020-00212-4 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Lu, Qiang
He, Wenwen
Lu, Yi
Zhu, Xiangjia
Morphological features of anterior segment: factors influencing intraocular pressure after cataract surgery in nanophthalmos
title Morphological features of anterior segment: factors influencing intraocular pressure after cataract surgery in nanophthalmos
title_full Morphological features of anterior segment: factors influencing intraocular pressure after cataract surgery in nanophthalmos
title_fullStr Morphological features of anterior segment: factors influencing intraocular pressure after cataract surgery in nanophthalmos
title_full_unstemmed Morphological features of anterior segment: factors influencing intraocular pressure after cataract surgery in nanophthalmos
title_short Morphological features of anterior segment: factors influencing intraocular pressure after cataract surgery in nanophthalmos
title_sort morphological features of anterior segment: factors influencing intraocular pressure after cataract surgery in nanophthalmos
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495875/
https://www.ncbi.nlm.nih.gov/pubmed/32974413
http://dx.doi.org/10.1186/s40662-020-00212-4
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