Prey for the Proteasome: Targeted Protein Degradation—A Medicinal Chemist's Perspective

Targeted protein degradation (TPD), the ability to control a proteins fate by triggering its degradation in a highly selective and effective manner, has created tremendous excitement in chemical biology and drug discovery within the past decades. The TPD field is spearheaded by small molecule induce...

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Detalles Bibliográficos
Autores principales: Luh, Laura M., Scheib, Ulrike, Juenemann, Katrin, Wortmann, Lars, Brands, Michael, Cromm, Philipp M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496094/
https://www.ncbi.nlm.nih.gov/pubmed/32428344
http://dx.doi.org/10.1002/anie.202004310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496094/
https://www.ncbi.nlm.nih.gov/pubmed/32428344
http://dx.doi.org/10.1002/anie.202004310

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