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Prey for the Proteasome: Targeted Protein Degradation—A Medicinal Chemist's Perspective
Targeted protein degradation (TPD), the ability to control a proteins fate by triggering its degradation in a highly selective and effective manner, has created tremendous excitement in chemical biology and drug discovery within the past decades. The TPD field is spearheaded by small molecule induce...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496094/ https://www.ncbi.nlm.nih.gov/pubmed/32428344 http://dx.doi.org/10.1002/anie.202004310 |