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Pilot Study in Temporary Peripheral Nerve Stimulation in Oncologic Pain

OBJECTIVES: Temporary, percutaneous peripheral nerve stimulation (PNS) has been shown to provide analgesia for acute postoperative pain, postamputation pain, and low back pain. The implanted device stimulates the neural target for up to 60 days at which point the leads are extracted. Patients have d...

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Autores principales: Mainkar, Ojas, Sollo, Che Antonio, Chen, Grant, Legler, Aron, Gulati, Amitabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496167/
https://www.ncbi.nlm.nih.gov/pubmed/32185844
http://dx.doi.org/10.1111/ner.13139
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author Mainkar, Ojas
Sollo, Che Antonio
Chen, Grant
Legler, Aron
Gulati, Amitabh
author_facet Mainkar, Ojas
Sollo, Che Antonio
Chen, Grant
Legler, Aron
Gulati, Amitabh
author_sort Mainkar, Ojas
collection PubMed
description OBJECTIVES: Temporary, percutaneous peripheral nerve stimulation (PNS) has been shown to provide analgesia for acute postoperative pain, postamputation pain, and low back pain. The implanted device stimulates the neural target for up to 60 days at which point the leads are extracted. Patients have demonstrated prolonged analgesia continuing after extraction of the leads. The purpose of this case series is to demonstrate peripheral neural targets that could feasibly be used to treat various pain syndromes prevalent in the oncologic population. MATERIALS AND METHODS: A temporary, percutaneous PNS was implanted under ultrasound guidance in 12 oncologic chronic pain patients seen in an outpatient pain clinic who had failed medical and/or interventional management. The device was implanted for up to 60 days. Clinical progress of pain and functional capacity was monitored through regular clinical visits. RESULTS: The case series presents seven successful cases of implementation of the PNS to treat oncologic pain. Three of these cases demonstrate targeting of proximal spinal nerves to treat truncal neuropathic pain and lumbar radicular pain. The four remaining cases demonstrate successful targeting of other peripheral nerves and brachial plexus. We also share five failed cases without adequate pain relief with PNS. CONCLUSIONS: PNS has potential uses in the treatment of oncologic pain. Further high‐quality studies should be designed to further elucidate use of the PNS to treat oncologic pain.
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spelling pubmed-74961672020-09-25 Pilot Study in Temporary Peripheral Nerve Stimulation in Oncologic Pain Mainkar, Ojas Sollo, Che Antonio Chen, Grant Legler, Aron Gulati, Amitabh Neuromodulation Clinical Research OBJECTIVES: Temporary, percutaneous peripheral nerve stimulation (PNS) has been shown to provide analgesia for acute postoperative pain, postamputation pain, and low back pain. The implanted device stimulates the neural target for up to 60 days at which point the leads are extracted. Patients have demonstrated prolonged analgesia continuing after extraction of the leads. The purpose of this case series is to demonstrate peripheral neural targets that could feasibly be used to treat various pain syndromes prevalent in the oncologic population. MATERIALS AND METHODS: A temporary, percutaneous PNS was implanted under ultrasound guidance in 12 oncologic chronic pain patients seen in an outpatient pain clinic who had failed medical and/or interventional management. The device was implanted for up to 60 days. Clinical progress of pain and functional capacity was monitored through regular clinical visits. RESULTS: The case series presents seven successful cases of implementation of the PNS to treat oncologic pain. Three of these cases demonstrate targeting of proximal spinal nerves to treat truncal neuropathic pain and lumbar radicular pain. The four remaining cases demonstrate successful targeting of other peripheral nerves and brachial plexus. We also share five failed cases without adequate pain relief with PNS. CONCLUSIONS: PNS has potential uses in the treatment of oncologic pain. Further high‐quality studies should be designed to further elucidate use of the PNS to treat oncologic pain. John Wiley & Sons, Inc. 2020-03-17 2020-08 /pmc/articles/PMC7496167/ /pubmed/32185844 http://dx.doi.org/10.1111/ner.13139 Text en © 2020 The Authors. Neuromodulation: Technology at the Neural Interface published by Wiley Periodicals LLC. on behalf of International Neuromodulation Society. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Clinical Research
Mainkar, Ojas
Sollo, Che Antonio
Chen, Grant
Legler, Aron
Gulati, Amitabh
Pilot Study in Temporary Peripheral Nerve Stimulation in Oncologic Pain
title Pilot Study in Temporary Peripheral Nerve Stimulation in Oncologic Pain
title_full Pilot Study in Temporary Peripheral Nerve Stimulation in Oncologic Pain
title_fullStr Pilot Study in Temporary Peripheral Nerve Stimulation in Oncologic Pain
title_full_unstemmed Pilot Study in Temporary Peripheral Nerve Stimulation in Oncologic Pain
title_short Pilot Study in Temporary Peripheral Nerve Stimulation in Oncologic Pain
title_sort pilot study in temporary peripheral nerve stimulation in oncologic pain
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496167/
https://www.ncbi.nlm.nih.gov/pubmed/32185844
http://dx.doi.org/10.1111/ner.13139
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