Cargando…

Implantation of the clinical‐grade human neural stem cell line, CTX0E03, rescues the behavioral and pathological deficits in the quinolinic acid‐lesioned rodent model of Huntington's disease

Huntington's disease (HD) is a devastating, autosomal‐dominant neurodegenerative disease, for which there are currently no disease‐modifying therapies. Clinical trials to replace the damaged striatal medium spiny neurons (MSNs) have been attempted in the past two decades but have met with only...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoon, Yongwoo, Kim, Hyun Sook, Jeon, Iksoo, Noh, Jeong‐Eun, Park, Hyun Jung, Lee, Suji, Park, In‐Hyun, Stevanato, Lara, Hicks, Caroline, Corteling, Randolph, Barker, Roger A., Sinden, John D., Song, Jihwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2020
Materias:	Regenerative Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496241/ https://www.ncbi.nlm.nih.gov/pubmed/32374064 http://dx.doi.org/10.1002/stem.3191

Ejemplares similares

Neural Transplants From Human Induced Pluripotent Stem Cells Rescue the Pathology and Behavioral Defects in a Rodent Model of Huntington’s Disease
por: Yoon, Yongwoo, et al.
Publicado: (2020)

c-MycER(TAM )transgene silencing in a genetically modified human neural stem cell line implanted into MCAo rodent brain
por: Stevanato, Lara, et al.
Publicado: (2009)

Intracerebral Transplantation of BDNF-overexpressing Human Neural Stem Cells (HB1.F3.BDNF) Promotes Migration, Differentiation and Functional Recovery in a Rodent Model of Huntington's Disease
por: Kim, Hyun Sook, et al.
Publicado: (2020)

Human Neural Stem Cell Therapy for Chronic Ischemic Stroke: Charting Progress from Laboratory to Patients
por: Sinden, John D., et al.
Publicado: (2017)

In Vivo Roles of a Patient-Derived Induced Pluripotent Stem Cell Line (HD72-iPSC) in the YAC128 Model of Huntington’s Disease
por: Jeon, Iksoo, et al.
Publicado: (2014)

Intracerebral transplantation of HLA‐homozygous human iPSC‐derived neural precursors ameliorates the behavioural and pathological deficits in a rodent model of ischaemic stroke
por: Noh, Jeong‐Eun, et al.
Publicado: (2020)

Intracerebral Transplants of GMP-Grade Human Umbilical Cord-Derived Mesenchymal Stromal Cells Effectively Treat Subacute-Phase Ischemic Stroke in a Rodent Model
por: Noh, Jeong-Eun, et al.
Publicado: (2020)

Neural stem cells derived from the developing forebrain of YAC128 mice exhibit pathological features of Huntington’s disease
por: Li, Endan, et al.
Publicado: (2020)

Application of Tonsil‐Derived Mesenchymal Stem Cells in Tissue Regeneration: Concise Review
por: Oh, Se‐Young, et al.
Publicado: (2019)

Multimodal Therapeutic Effects of Neural Precursor Cells Derived from Human-Induced Pluripotent Stem Cells through Episomal Plasmid-Based Reprogramming in a Rodent Model of Ischemic Stroke
por: Oh, Seung-Hun, et al.
Publicado: (2020)

SUPT4H1-edited stem cell therapy rescues neuronal dysfunction in a mouse model for Huntington’s disease
por: Park, Hyun Jung, et al.
Publicado: (2022)

Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model
por: Lee, Hyunah, et al.
Publicado: (2020)

Differentiation of a Human Neural Stem Cell Line on Three Dimensional Cultures, Analysis of MicroRNA and Putative Target Genes
por: Stevanato, Lara, et al.
Publicado: (2015)

Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer’s model
por: Reinitz, Felicia, et al.
Publicado: (2022)

Author Correction : SUPT4H1-edited stem cell therapy rescues neuronal dysfunction in a mouse model for Huntington’s disease
por: Park, Hyun Jung, et al.
Publicado: (2022)

Stem cell transplantation rescued a primary open-angle glaucoma mouse model
por: Xiong, Siqi, et al.
Publicado: (2021)

Activation of Notch Signaling During Ex Vivo Expansion Maintains Donor Muscle Cell Engraftment, ,
por: Parker, Maura H., et al.
Publicado: (2012)

Stem Cells and Cartilage Development: Complexities of a Simple Tissue
por: Hollander, Anthony P, et al.
Publicado: (2010)

Allogeneic Periodontal Ligament Stem Cell Therapy for Periodontitis in Swine
por: Ding, Gang, et al.
Publicado: (2010)

Nitric Oxide Sustains Long-Term Skeletal Muscle Regeneration by Regulating Fate of Satellite Cells Via Signaling Pathways Requiring Vangl2 and Cyclic GMP
por: Buono, Roberta, et al.
Publicado: (2012)

Inhibition of T Cell Protein Tyrosine Phosphatase Enhances Interleukin-18-Dependent Hematopoietic Stem Cell Expansion
por: Bourdeau, Annie, et al.
Publicado: (2013)

HIF-2α Suppresses p53 to Enhance the Stemness and Regenerative Potential of Human Embryonic Stem Cells
por: Das, Bikul, et al.
Publicado: (2012)

PACAP38/PAC1 Signaling Induces Bone Marrow-Derived Cells Homing to Ischemic Brain
por: Lin, Chen-Huan, et al.
Publicado: (2015)

Combination of miRNA499 and miRNA133 Exerts a Synergic Effect on Cardiac Differentiation
por: Pisano, Federica, et al.
Publicado: (2015)

Cellular Reprogramming Allows Generation of Autologous Hematopoietic Progenitors From AML Patients That Are Devoid of Patient-Specific Genomic Aberrations
por: Salci, Kyle R, et al.
Publicado: (2015)

Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel From Embryonic Stem Cell‐Derived Self‐Forming Retina
por: Lakowski, Jorn, et al.
Publicado: (2015)

Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation
por: Tassoni, Alessia, et al.
Publicado: (2015)

Induced Pluripotent Stem Cells Restore Function in a Human Cell Loss Model of Open-Angle Glaucoma
por: Abu-Hassan, Diala W, et al.
Publicado: (2015)

Transient Canonical Wnt Stimulation Enriches Human Bone Marrow Mononuclear Cell Isolates for Osteoprogenitors
por: Janeczek, Agnieszka A., et al.
Publicado: (2015)

An exploratory randomized control study of combination cytokine and adult autologous bone marrow progenitor cell administration in patients with ischaemic cardiomyopathy: the REGENERATE‐IHD clinical trial
por: Choudhury, Tawfiq, et al.
Publicado: (2016)

Neuroprotective Effects of Human Mesenchymal Stem Cells and Platelet‐Derived Growth Factor on Human Retinal Ganglion Cells
por: Osborne, Andrew, et al.
Publicado: (2017)

Differential Regulation of Human Bone Marrow Mesenchymal Stromal Cell Chondrogenesis by Hypoxia Inducible Factor‐1α Hydroxylase Inhibitors
por: Taheem, Dheraj K., et al.
Publicado: (2018)

Follistatin‐Like 3 Enhances the Function of Endothelial Cells Derived from Pluripotent Stem Cells by Facilitating β‐Catenin Nuclear Translocation Through Inhibition of Glycogen Synthase Kinase‐3β Activity
por: Kelaini, Sophia, et al.
Publicado: (2018)

The Vasoreparative Function of Myeloid Angiogenic Cells Is Impaired in Diabetes Through the Induction of IL1β
por: Chambers, Sarah E. J., et al.
Publicado: (2018)

Isolation of Human Photoreceptor Precursors via a Cell Surface Marker Panel from Stem Cell‐Derived Retinal Organoids and Fetal Retinae
por: Lakowski, Jörn, et al.
Publicado: (2018)

Concise Review: The Regenerative Journey of Pericytes Toward Clinical Translation
por: Cathery, William, et al.
Publicado: (2018)

Enhanced Function of Induced Pluripotent Stem Cell‐Derived Endothelial Cells Through ESM1 Signaling
por: Vilà‐González, Marta, et al.
Publicado: (2018)

Quaking Is a Key Regulator of Endothelial Cell Differentiation, Neovascularization, and Angiogenesis
por: Cochrane, Amy, et al.
Publicado: (2017)

Human Cartilage‐Derived Progenitors Resist Terminal Differentiation and Require CXCR4 Activation to Successfully Bridge Meniscus Tissue Tears
por: Jayasuriya, Chathuraka T., et al.
Publicado: (2018)

Concise Review: Stem/Progenitor Cell Proteoglycans Decorated with 7‐D‐4, 4‐C‐3, and 3‐B‐3(‐) Chondroitin Sulfate Motifs Are Morphogenetic Markers of Tissue Development
por: Hayes, Anthony J., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_62evbftqnrqu4h5tgtkfpis2sv