Activity‐Directed Synthesis of Inhibitors of the p53/hDM2 Protein–Protein Interaction

Protein–protein interactions (PPIs) provide a rich source of potential targets for drug discovery and biomedical science research. However, the identification of structural‐diverse starting points for discovery of PPI inhibitors remains a significant challenge. Activity‐directed synthesis (ADS), a f...

Descripción completa

Detalles Bibliográficos
Autores principales: Green, Adam I., Hobor, Fruzsina, Tinworth, Christopher P., Warriner, Stuart, Wilson, Andrew J., Nelson, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496268/
https://www.ncbi.nlm.nih.gov/pubmed/32458465
http://dx.doi.org/10.1002/chem.202002153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496268/
https://www.ncbi.nlm.nih.gov/pubmed/32458465
http://dx.doi.org/10.1002/chem.202002153

Ejemplares similares