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Activity‐Directed Synthesis of Inhibitors of the p53/hDM2 Protein–Protein Interaction
Protein–protein interactions (PPIs) provide a rich source of potential targets for drug discovery and biomedical science research. However, the identification of structural‐diverse starting points for discovery of PPI inhibitors remains a significant challenge. Activity‐directed synthesis (ADS), a f...
Autores principales: | Green, Adam I., Hobor, Fruzsina, Tinworth, Christopher P., Warriner, Stuart, Wilson, Andrew J., Nelson, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496268/ https://www.ncbi.nlm.nih.gov/pubmed/32458465 http://dx.doi.org/10.1002/chem.202002153 |
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