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Technical Note: Comprehensive performance tests of the first clinical real‐time motion tracking and compensation system using MLC and jaws

PURPOSE: To evaluate the performance of the first clinical real‐time motion tracking and compensation system using multileaf collimator (MLC) and jaws during helical tomotherapy delivery. METHODS: Appropriate mechanical and dosimetry tests were performed on the first clinical real‐time motion tracki...

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Autores principales: Chen, Guang‐Pei, Tai, An, Keiper, Timothy D., Lim, Sara, Li, X. Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496291/
https://www.ncbi.nlm.nih.gov/pubmed/32277477
http://dx.doi.org/10.1002/mp.14171
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author Chen, Guang‐Pei
Tai, An
Keiper, Timothy D.
Lim, Sara
Li, X. Allen
author_facet Chen, Guang‐Pei
Tai, An
Keiper, Timothy D.
Lim, Sara
Li, X. Allen
author_sort Chen, Guang‐Pei
collection PubMed
description PURPOSE: To evaluate the performance of the first clinical real‐time motion tracking and compensation system using multileaf collimator (MLC) and jaws during helical tomotherapy delivery. METHODS: Appropriate mechanical and dosimetry tests were performed on the first clinical real‐time motion tracking system (Synchrony on Radixact, Accuray Inc) recently installed in our institution. kV radiography dose was measured by CTDIw using a pencil chamber. Changes of beam characteristics with jaw offset and MLC leaf shift were evaluated. Various dosimeters and phantoms including A1SL ion chamber (Standard Imaging), Gafchromic EBT3 films (Ashland), TomoPhantom (Med Cal), ArcCheck (Sun Nuclear), Delta4 (ScandiDos), with fiducial or high contrast inserts, placed on two dynamical motion platforms (CIRS dynamic motion‐CIRS, Hexamotion‐ScandiDos), were used to assess the dosimetric accuracy of the available Synchrony modalities: fiducial tracking with nonrespiratory motion (FNR), fiducial tracking with respiratory modeling (FR), and fiducial free (e.g., lung tumor tracking) with respiratory modeling (FFR). Motion detection accuracy of a tracking target, defined as the difference between the predicted and instructed target positions, was evaluated with the root mean square (RMS). The dose accuracy of motion compensation was evaluated by verifying the dose output constancy and by comparing measured and planned (predicted) three‐dimensional (3D) dose distributions based on gamma analysis. RESULTS: The measured CTDIw for a single radiograph with a 120 kVp and 1.6 mAs protocol was 0.084 mGy, implying a low imaging dose of 8.4 mGy for a typical Synchrony motion tracking fraction with 100 radiographs. The dosimetric effect of the jaw swing or MLC leaf shift was minimal on depth dose (<0.5%) and was <2% on both beam profile width and output for typical motions. The motion detection accuracies, that is, RMS, were 0.84, 1.13, and 0.48 mm for FNR, FR, and FFR, respectively, well within the 1.5 mm recommended tolerance. Dose constancy with Synchrony was found to be within 2%. The gamma passing rates of 3D dose measurements for a variety of Synchrony plans were well within the acceptable level. CONCLUSIONS: The motion tracking and compensation using kV radiography, MLC shifting, and jaw swing during helical tomotherapy delivery was tested to be mechanically and dosimetrically accurate for clinical use.
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spelling pubmed-74962912020-09-25 Technical Note: Comprehensive performance tests of the first clinical real‐time motion tracking and compensation system using MLC and jaws Chen, Guang‐Pei Tai, An Keiper, Timothy D. Lim, Sara Li, X. Allen Med Phys THERAPEUTIC INTERVENTIONS PURPOSE: To evaluate the performance of the first clinical real‐time motion tracking and compensation system using multileaf collimator (MLC) and jaws during helical tomotherapy delivery. METHODS: Appropriate mechanical and dosimetry tests were performed on the first clinical real‐time motion tracking system (Synchrony on Radixact, Accuray Inc) recently installed in our institution. kV radiography dose was measured by CTDIw using a pencil chamber. Changes of beam characteristics with jaw offset and MLC leaf shift were evaluated. Various dosimeters and phantoms including A1SL ion chamber (Standard Imaging), Gafchromic EBT3 films (Ashland), TomoPhantom (Med Cal), ArcCheck (Sun Nuclear), Delta4 (ScandiDos), with fiducial or high contrast inserts, placed on two dynamical motion platforms (CIRS dynamic motion‐CIRS, Hexamotion‐ScandiDos), were used to assess the dosimetric accuracy of the available Synchrony modalities: fiducial tracking with nonrespiratory motion (FNR), fiducial tracking with respiratory modeling (FR), and fiducial free (e.g., lung tumor tracking) with respiratory modeling (FFR). Motion detection accuracy of a tracking target, defined as the difference between the predicted and instructed target positions, was evaluated with the root mean square (RMS). The dose accuracy of motion compensation was evaluated by verifying the dose output constancy and by comparing measured and planned (predicted) three‐dimensional (3D) dose distributions based on gamma analysis. RESULTS: The measured CTDIw for a single radiograph with a 120 kVp and 1.6 mAs protocol was 0.084 mGy, implying a low imaging dose of 8.4 mGy for a typical Synchrony motion tracking fraction with 100 radiographs. The dosimetric effect of the jaw swing or MLC leaf shift was minimal on depth dose (<0.5%) and was <2% on both beam profile width and output for typical motions. The motion detection accuracies, that is, RMS, were 0.84, 1.13, and 0.48 mm for FNR, FR, and FFR, respectively, well within the 1.5 mm recommended tolerance. Dose constancy with Synchrony was found to be within 2%. The gamma passing rates of 3D dose measurements for a variety of Synchrony plans were well within the acceptable level. CONCLUSIONS: The motion tracking and compensation using kV radiography, MLC shifting, and jaw swing during helical tomotherapy delivery was tested to be mechanically and dosimetrically accurate for clinical use. John Wiley and Sons Inc. 2020-05-11 2020-07 /pmc/articles/PMC7496291/ /pubmed/32277477 http://dx.doi.org/10.1002/mp.14171 Text en © 2020 The Authors. Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle THERAPEUTIC INTERVENTIONS
Chen, Guang‐Pei
Tai, An
Keiper, Timothy D.
Lim, Sara
Li, X. Allen
Technical Note: Comprehensive performance tests of the first clinical real‐time motion tracking and compensation system using MLC and jaws
title Technical Note: Comprehensive performance tests of the first clinical real‐time motion tracking and compensation system using MLC and jaws
title_full Technical Note: Comprehensive performance tests of the first clinical real‐time motion tracking and compensation system using MLC and jaws
title_fullStr Technical Note: Comprehensive performance tests of the first clinical real‐time motion tracking and compensation system using MLC and jaws
title_full_unstemmed Technical Note: Comprehensive performance tests of the first clinical real‐time motion tracking and compensation system using MLC and jaws
title_short Technical Note: Comprehensive performance tests of the first clinical real‐time motion tracking and compensation system using MLC and jaws
title_sort technical note: comprehensive performance tests of the first clinical real‐time motion tracking and compensation system using mlc and jaws
topic THERAPEUTIC INTERVENTIONS
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496291/
https://www.ncbi.nlm.nih.gov/pubmed/32277477
http://dx.doi.org/10.1002/mp.14171
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