Cargando…

Reduced Caudal Type Homeobox 2 (CDX2) Promoter Methylation Is Associated with Curcumin’s Suppressive Effects on Epithelial-Mesenchymal Transition in Colorectal Cancer Cells

BACKGROUND: Curcumin is a component of Curcuma longa with various biological activities. The present study aimed to investigate curcumin’s inhibitory effects on epithelial-mesenchymal transition (EMT) in colorectal cancer (CRC) cells and possible mechanisms of action underlying these effects. MATERI...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Ting, Yang, Chun, Xi, Zhenli, Chen, Fen, Li, Hailin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2020
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496454/ https://www.ncbi.nlm.nih.gov/pubmed/32893845 http://dx.doi.org/10.12659/MSM.926443

Ejemplares similares

Curcumin Inhibits Cell Viability and Increases Apoptosis of SW620 Human Colon Adenocarcinoma Cells via the Caudal Type Homeobox-2 (CDX2)/Wnt/β-Catenin Pathway
por: Jiang, Xinger, et al.
Publicado: (2019)

Inhibitory Effects of Plumbagin on Retinal Pigment Epithelial Cell Epithelial-Mesenchymal Transition In Vitro and In Vivo
por: Chen, Haitin, et al.
Publicado: (2018)

Interaction Between Ezrin and Cortactin in Promoting Epithelial to Mesenchymal Transition in Breast Cancer Cells
por: He, Jing, et al.
Publicado: (2017)

Anti-Tumor Effects of Paeoniflorin on Epithelial-To-Mesenchymal Transition in Human Colorectal Cancer Cells
por: Zhang, Jia-Wei, et al.
Publicado: (2018)

Prognostic Significance of Zinc Finger E-Box-Binding Homeobox Family in Glioblastoma
por: Chen, Peng, et al.
Publicado: (2018)

Fascin Induces Epithelial-Mesenchymal Transition of Cholangiocarcinoma Cells by Regulating Wnt/β-Catenin Signaling
por: Mao, Xianhai, et al.
Publicado: (2016)

High Expression of Peroxiredoxin 1 Is Associated with Epithelial-Mesenchymal Transition Marker and Poor Prognosis in Gastric Cancer
por: Yu, Wei, et al.
Publicado: (2018)

Protective Effect of Anthocyanin on Paraquat-Induced Apoptosis and Epithelial-Mesenchymal Transition in Alveolar Type II Cells
por: Wang, Zhihua, et al.
Publicado: (2018)

Upregulation of FAM3B Promotes Cisplatin Resistance in Gastric Cancer by Inducing Epithelial-Mesenchymal Transition
por: Song, Chun, et al.
Publicado: (2020)

Overexpression of Tripartite Motif Conaining 55 (TRIM55) Inhibits Migration and Invasion of Hepatocellular Carcinoma (HCC) Cells via Epithelial-Mesenchymal Transition and Matrix Metalloproteinase-2 (MMP2)
por: Li, Xinyu, et al.
Publicado: (2019)

Transduced caudal‐type homeobox (CDX) 2/CDX1 can induce growth inhibition on CDX‐deficient gastric cancer by rapid intestinal differentiation
por: Nakayama, Chiemi, et al.
Publicado: (2018)

Cervical Cancer Cell Growth, Drug Resistance, and Epithelial-Mesenchymal Transition Are Suppressed by γ-Secretase Inhibitor RO4929097
por: Wang, Lu, et al.
Publicado: (2018)

Doxorubicin-Induced Cancer Cell Senescence Shows a Time Delay Effect and Is Inhibited by Epithelial-Mesenchymal Transition (EMT)
por: Hu, Xuerui, et al.
Publicado: (2019)

Long Noncoding RNA TCONS_00068220 Promotes Breast Cancer Progression by Regulating Epithelial-Mesenchymal Transition Marker E-Cadherin
por: Liu, Xiao, et al.
Publicado: (2021)

High Glucose Promotes Epithelial-Mesenchymal Transition, Migration and Invasion in A20 Murine Diffuse Large B-Cell Lymphoma Cells Through Increased Expression of High Mobility Group AT-Hook 2 (HMGA2)
por: Wang, Ya, et al.
Publicado: (2019)

Long Non-Coding RNA (LncRNA) HOXA11-AS Promotes Breast Cancer Invasion and Metastasis by Regulating Epithelial-Mesenchymal Transition
por: Li, Wenlei, et al.
Publicado: (2017)

MicroRNA-145 Inhibits Cell Migration and Invasion and Regulates Epithelial-Mesenchymal Transition (EMT) by Targeting Connective Tissue Growth Factor (CTGF) in Esophageal Squamous Cell Carcinoma
por: Han, Qiang, et al.
Publicado: (2016)

Mammalian Target of Rapamycin (mTOR) Regulates Transforming Growth Factor-β(1) (TGF-β(1))-Induced Epithelial-Mesenchymal Transition via Decreased Pyruvate Kinase M2 (PKM2) Expression in Cervical Cancer Cells
por: Cheng, Ke-yan, et al.
Publicado: (2017)

Inhibitor of Differentiation 1 (ID1) Facilitates the Efficacy of Sorafenib in Non-Small Cell Lung Cancer Cells through Suppressing Epithelial to Mesenchymal Transition
por: Zhao, Yu-xiao, et al.
Publicado: (2020)

KIAA1199, a Target of MicoRNA-486-5p, Promotes Papillary Thyroid Cancer Invasion by Influencing Epithelial-Mesenchymal Transition (EMT)
por: Jiao, Xuehua, et al.
Publicado: (2019)

The Effects of Interleukin-33 (IL-33) on Osteosarcoma Cell Viability, Apoptosis, and Epithelial-Mesenchymal Transition are Mediated Through the PI3K/AKT Pathway
por: Wang, Shenyu, et al.
Publicado: (2020)

Calcium-Activated Chloride Channel A4 (CLCA4) Plays Inhibitory Roles in Invasion and Migration Through Suppressing Epithelial-Mesenchymal Transition via PI3K/AKT Signaling in Colorectal Cancer
por: Chen, Hua, et al.
Publicado: (2019)

Curcumin Derivative C086 Combined with Cisplatin Inhibits Proliferation of Osteosarcoma Cells
por: Jiang, Xi, et al.
Publicado: (2020)

Kinesin Family Member C1 (KIFC1) Regulated by Centrosome Protein E (CENPE) Promotes Proliferation, Migration, and Epithelial-Mesenchymal Transition of Ovarian Cancer
por: Li, Jiangning, et al.
Publicado: (2020)

Comparative Analysis of Gastrointestinal Microbiota Between Normal and Caudal-Related Homeobox 2 (Cdx2) Transgenic Mice
por: Sakamoto, Hirotsugu, et al.
Publicado: (2015)

Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer
por: Li, Ji-Min, et al.
Publicado: (2020)

Ginsenoside Rg3 Reduces Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor-β1 by Inactivation of AKT in HMrSV5 Peritoneal Mesothelial Cells
por: Yan, Xu, et al.
Publicado: (2019)

Motor Neuron and Pancreas Homeobox 1 (MNX1) Is Involved in Promoting Squamous Cervical Cancer Proliferation via Regulating Cyclin E
por: Xiao, Li, et al.
Publicado: (2019)

P53 and Protein Phosphorylation Regulate the Oncogenic Role of Epithelial Cell Transforming 2 (ECT2)
por: Chen, Yan, et al.
Publicado: (2017)

1,25-Dihydroxyvitamin D3 Prevents Epithelial-Mesenchymal Transition of HMrSV5 Human Peritoneal Mesothelial Cells by Inhibiting Histone Deacetylase 3 (HDAC3) and Increasing Vitamin D Receptor (VDR) Expression Through the Wnt/β-Catenin Signaling Pathway
por: Liu, Kang-Han, et al.
Publicado: (2019)

Downregulation of SEMA4C Inhibit Epithelial-Mesenchymal Transition (EMT) and the Invasion and Metastasis of Cervical Cancer Cells via Inhibiting Transforming Growth Factor-beta 1 (TGF-β1)-Induced Hela cells p38 Mitogen-Activated Protein Kinase (MAPK) Activation
por: Yang, Lilan, et al.
Publicado: (2020)

SOX18 Affects Cell Viability, Migration, Invasiveness, and Apoptosis in Hepatocellular Carcinoma (HCC) Cells by Participating in Epithelial-to-Mesenchymal Transition (EMT) Progression and Adenosine Monophosphate Activated Protein Kinase (AMPK)/Mammalian Target of Rapamycin (mTOR)
por: Sun, Yanni, et al.
Publicado: (2019)

Curcumin Treatment is Associated with Increased Expression of the N-Methyl-D-Aspartate Receptor (NMDAR) Subunit, NR2A, in a Rat PC12 Cell Line Model of Alzheimer’s Disease Treated with the Acetyl Amyloid-β Peptide, Aβ(25–35)
por: Qian, Wei, et al.
Publicado: (2018)

Caudal Homeobox Protein Cdx-2 Cooperates with Wnt Pathway to Regulate Claudin-1 Expression in Colon Cancer Cells
por: Bhat, Ajaz A., et al.
Publicado: (2012)

Curcumin Suppresses Apoptosis and Inflammation in Hypoxia/Reperfusion-Exposed Neurons via Wnt Signaling Pathway
por: Zhou, Jiaxing, et al.
Publicado: (2020)

MiR-494 Inhibits Epithelial Ovarian Cancer Growth by Targeting c-Myc
por: Yuan, Jialing, et al.
Publicado: (2016)

Role of B-Cell Lymphoma 2 Ovarian Killer (BOK) in Acute Toxicity of Human Lung Epithelial Cells Caused by Cadmium Chloride
por: Zhang, Fang, et al.
Publicado: (2019)

Curcumin Induces Autophagy via Inhibition of Yes-Associated Protein (YAP) in Human Colon Cancer Cells
por: Zhu, Jing, et al.
Publicado: (2018)

CYP2C9, a Metabolic CYP450s Enzyme, Plays Critical Roles in Activating Ellagic Acid in Human Intestinal Epithelial Cells
por: Gu, Yang, et al.
Publicado: (2020)

Bcl-2 19-kDa Interacting Protein 3 (BNIP3)-Mediated Mitophagy Attenuates Intermittent Hypoxia-Induced Human Renal Tubular Epithelial Cell Injury
por: Zhang, Xiao-Bin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qb0f0ahpej6vdqt725g22hl4id