Cargando…

Whole blood survival motor neuron protein levels correlate with severity of denervation in spinal muscular atrophy

INTRODUCTION: We sought to determine whether survival motor neuron (SMN) protein blood levels correlate with denervation and SMN2 copies in spinal muscular atrophy (SMA). METHODS: Using a mixed‐effect model, we tested associations between SMN levels, compound muscle action potential (CMAP), and SMN2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alves, Christiano R. R., Zhang, Ren, Johnstone, Alec J., Garner, Reid, Eichelberger, Eric J., Lepez, Salomé Da Silva Duarte, Yi, Vivian, Stevens, Victoria, Poxson, Rebekah, Schwartz, Rachel, Zaworski, Phillip, Swoboda, Kathryn J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2020
Materias:	Clinical Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496476/ https://www.ncbi.nlm.nih.gov/pubmed/32511765 http://dx.doi.org/10.1002/mus.26995

Ejemplares similares

Whole‐blood dysregulation of actin‐cytoskeleton pathway in adult spinal muscular atrophy patients
por: Siranosian, Jennifer J., et al.
Publicado: (2020)

Implications of circulating neurofilaments for spinal muscular atrophy treatment early in life: A case series
por: Alves, Christiano R.R., et al.
Publicado: (2021)

Increased systemic HSP70B levels in spinal muscular atrophy infants
por: Eichelberger, Eric J., et al.
Publicado: (2021)

Impaired kidney structure and function in spinal muscular atrophy
por: Nery, Flávia C., et al.
Publicado: (2019)

Base editing as a genetic treatment for spinal muscular atrophy
por: Alves, Christiano R. R., et al.
Publicado: (2023)

A Comparison of Three Electrophysiological Methods for the Assessment of Disease Status in a Mild Spinal Muscular Atrophy Mouse Model
por: Li, Jia, et al.
Publicado: (2014)

Ultrastructural characterization of peripheral denervation in a mouse model of Type III spinal muscular atrophy
por: Fulceri, Federica, et al.
Publicado: (2021)

Transferrin receptor 1 plays an important role in muscle development and denervation-induced muscular atrophy
por: Li, Ying, et al.
Publicado: (2020)

Emerging therapies and challenges in spinal muscular atrophy
por: Farrar, Michelle A., et al.
Publicado: (2017)

Identification of Potential miRNA-mRNA Regulatory Network in Denervated Muscular Atrophy by Bioinformatic Analysis
por: Wang, Jianhua, et al.
Publicado: (2022)

Biomarker for Spinal Muscular Atrophy: Expression of SMN in Peripheral Blood of SMA Patients and Healthy Controls
por: Czech, Christian, et al.
Publicado: (2015)

Muscular Atrophy and Sclerodermia
por: Nixon, J. A.
Publicado: (1903)

Muscle microRNAs in the cerebrospinal fluid predict clinical response to nusinersen therapy in type II and type III spinal muscular atrophy patients
por: Magen, Iddo, et al.
Publicado: (2022)

COVID-19 related muscle denervation atrophy
por: Bahouth, S., et al.
Publicado: (2021)

Oxidative stress-induced premature senescence and aggravated denervated skeletal muscular atrophy by regulating progerin–p53 interaction
por: Xiang, Yaoxian, et al.
Publicado: (2022)

Case of Marked Muscular Atrophy of Hands and Fore-Arms—Progressive Muscular Atrophy(?)
por: Ness, R. Barclay
Publicado: (1895)

Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study
por: Kolb, Stephen J., et al.
Publicado: (2016)

Intrathecal Injections in Children With Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience
por: Haché, Manon, et al.
Publicado: (2016)

Evaluation of potential effects of Plastin 3 overexpression and low-dose SMN-antisense oligonucleotides on putative biomarkers in spinal muscular atrophy mice
por: Strathmann, Eike A., et al.
Publicado: (2018)

Lipid hydroperoxides and oxylipins are mediators of denervation induced muscle atrophy
por: Brown, Jacob L., et al.
Publicado: (2022)

Progressive Muscular Atrophy with Recovery
por: Clarke, J. Michell
Publicado: (1888)

Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway
por: Wang, Yuan, et al.
Publicado: (2018)

Spinal muscular atrophy
por: D'Amico, Adele, et al.
Publicado: (2011)

Progressive Muscular Atrophy
por: Omar, A.
Publicado: (1947)

Progressive Muscular Atrophy
por: Omar, A.
Publicado: (1947)

Progressive Muscular Atrophy
por: Omer, M. A.
Publicado: (1949)

Progressive Muscular Atrophy
Publicado: (1874)

Muscular Atrophy and Sclerodermia
Publicado: (1904)

Acute Muscular Atrophy
por: Haddon, John
Publicado: (1870)

Case of Muscular Atrophy
por: Kersey, V.
Publicado: (1871)

Denervation does not Induce Muscle Atrophy Through Oxidative Stress
por: Pigna, Eva, et al.
Publicado: (2017)

Natural Compounds Attenuate Denervation-Induced Skeletal Muscle Atrophy
por: Shirakawa, Tomohiko, et al.
Publicado: (2021)

Delayed denervation-induced muscle atrophy in Opg knockout mice
por: Zhang, Mingming, et al.
Publicado: (2023)

Denervation Atrophy of Skeletal Muscle is Not Influenced by Numb Levels in Mice
por: Aslan, Abdurrahman, et al.
Publicado: (2023)

Massachusetts’ Findings from Statewide Newborn Screening for Spinal Muscular Atrophy
por: Hale, Jaime E., et al.
Publicado: (2021)

Update on Biomarkers in Spinal Muscular Atrophy
por: Pino, Megan G, et al.
Publicado: (2021)

Phase II Open Label Study of Valproic Acid in Spinal Muscular Atrophy
por: Swoboda, Kathryn J., et al.
Publicado: (2009)

Clinical Commentary: Obstetric and Respiratory Management of Pregnancy with Severe Spinal Muscular Atrophy
por: Flunt, Daniel, et al.
Publicado: (2009)

Muscle contractility in spinobulbar muscular atrophy
por: Dahlqvist, Julia R., et al.
Publicado: (2019)

Sociodemographic and clinical characteristics and access to health care in patients with spinal muscular atrophy in Argentina
por: Vazquez, Gabriel Adolfo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hanonuee22l9arqaf6d0pqm432