Modular Medical Imaging Agents Based on Azide–Alkyne Huisgen Cycloadditions: Synthesis and Pre‐Clinical Evaluation of (18)F‐Labeled PSMA‐Tracers for Prostate Cancer Imaging

Since the seminal contribution of Rolf Huisgen to develop the [3+2] cycloaddition of 1,3‐dipolar compounds, its azide–alkyne variant has established itself as the key step in numerous organic syntheses and bioorthogonal processes in materials science and chemical biology. In the present study, the c...

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Detalles Bibliográficos
Autores principales: Böhmer, Verena I., Szymanski, Wiktor, van den Berg, Keimpe‐Oeds, Mulder, Chantal, Kobauri, Piermichele, Helbert, Hugo, van der Born, Dion, Reeβing, Friederike, Huizing, Anja, Klopstra, Marten, Samplonius, Douwe F., Antunes, Ines F., Sijbesma, Jürgen W. A., Luurtsema, Gert, Helfrich, Wijnand, Visser, Ton J., Feringa, Ben L., Elsinga, Philip H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496508/
https://www.ncbi.nlm.nih.gov/pubmed/32315486
http://dx.doi.org/10.1002/chem.202001795

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