Chemical simulation of hypoxia in donor cells improves development of somatic cell nuclear transfer‐derived embryos and increases abundance of transcripts related to glycolysis

To improve efficiency of somatic cell nuclear transfer (SCNT), it is necessary to modify differentiated donor cells to become more amendable for reprogramming by the oocyte cytoplasm. A key feature that distinguishes somatic/differentiated cells from embryonic/undifferentiated cells is cellular meta...

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Detalles Bibliográficos
Autores principales: Cecil, Raissa F., Chen, Paula R., Benne, Joshua A., Hord, Taylor K., Spate, Lee D., Samuel, Melissa S., Prather, Randall S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496615/
https://www.ncbi.nlm.nih.gov/pubmed/32558023
http://dx.doi.org/10.1002/mrd.23392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496615/
https://www.ncbi.nlm.nih.gov/pubmed/32558023
http://dx.doi.org/10.1002/mrd.23392

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