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Biological mechanisms underlying inter‐individual variation in factor VIII clearance in haemophilia

Previous studies have highlighted marked inter‐individual variations in factor VIII (FVIII) clearance between patients with haemophilia (PWH). The half‐life of infused FVIII has been reported to vary from as little as 5.3 hours in some adult PWH, up to as long as 28.8 hours in other individuals. The...

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Detalles Bibliográficos
Autores principales: Turecek, Peter L., Johnsen, Jill M., Pipe, Steven W., O'Donnell, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496649/
https://www.ncbi.nlm.nih.gov/pubmed/32596930
http://dx.doi.org/10.1111/hae.14078