Clinical and pathogenic aspects of the severe cutaneous adverse reaction epidermal necrolysis (EN)

The severe cutaneous adverse reaction epidermal necrolysis (EN) which includes toxic epidermal necrolysis and the milder Stevens‐Johnson syndrome is characterized by epidermal loss due to massive keratinocyte apoptosis and/or necroptosis. EN is often caused by a drug mediating a specific TCR‐HLA int...

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Detalles Bibliográficos
Autores principales: Kuijper, E.C., French, L.E., Tensen, C.P., Vermeer, M.H., Bouwes Bavinck, J.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496676/
https://www.ncbi.nlm.nih.gov/pubmed/32415695
http://dx.doi.org/10.1111/jdv.16339

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