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Electroreductive Cobalt‐Catalyzed Carboxylation: Cross‐Electrophile Electrocoupling with Atmospheric CO(2)
The chemical use of CO(2) as an inexpensive, nontoxic C1 synthon is of utmost topical interest in the context of carbon capture and utilization (CCU). We present the merger of cobalt catalysis and electrochemical synthesis for mild catalytic carboxylations of allylic chlorides with CO(2). Styrylacet...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496797/ https://www.ncbi.nlm.nih.gov/pubmed/32329560 http://dx.doi.org/10.1002/anie.202003218 |
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author | Ang, Nate W. J. Oliveira, João C. A. Ackermann, Lutz |
author_facet | Ang, Nate W. J. Oliveira, João C. A. Ackermann, Lutz |
author_sort | Ang, Nate W. J. |
collection | PubMed |
description | The chemical use of CO(2) as an inexpensive, nontoxic C1 synthon is of utmost topical interest in the context of carbon capture and utilization (CCU). We present the merger of cobalt catalysis and electrochemical synthesis for mild catalytic carboxylations of allylic chlorides with CO(2). Styrylacetic acid derivatives were obtained with moderate to good yields and good functional group tolerance. The thus‐obtained products are useful as versatile synthons of γ‐arylbutyrolactones. Cyclic voltammetry and in operando kinetic analysis were performed to provide mechanistic insights into the electrocatalytic carboxylation with CO(2). |
format | Online Article Text |
id | pubmed-7496797 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-74967972020-09-25 Electroreductive Cobalt‐Catalyzed Carboxylation: Cross‐Electrophile Electrocoupling with Atmospheric CO(2) Ang, Nate W. J. Oliveira, João C. A. Ackermann, Lutz Angew Chem Int Ed Engl Communications The chemical use of CO(2) as an inexpensive, nontoxic C1 synthon is of utmost topical interest in the context of carbon capture and utilization (CCU). We present the merger of cobalt catalysis and electrochemical synthesis for mild catalytic carboxylations of allylic chlorides with CO(2). Styrylacetic acid derivatives were obtained with moderate to good yields and good functional group tolerance. The thus‐obtained products are useful as versatile synthons of γ‐arylbutyrolactones. Cyclic voltammetry and in operando kinetic analysis were performed to provide mechanistic insights into the electrocatalytic carboxylation with CO(2). John Wiley and Sons Inc. 2020-05-28 2020-07-27 /pmc/articles/PMC7496797/ /pubmed/32329560 http://dx.doi.org/10.1002/anie.202003218 Text en © 2020 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Communications Ang, Nate W. J. Oliveira, João C. A. Ackermann, Lutz Electroreductive Cobalt‐Catalyzed Carboxylation: Cross‐Electrophile Electrocoupling with Atmospheric CO(2) |
title | Electroreductive Cobalt‐Catalyzed Carboxylation: Cross‐Electrophile Electrocoupling with Atmospheric CO(2)
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title_full | Electroreductive Cobalt‐Catalyzed Carboxylation: Cross‐Electrophile Electrocoupling with Atmospheric CO(2)
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title_fullStr | Electroreductive Cobalt‐Catalyzed Carboxylation: Cross‐Electrophile Electrocoupling with Atmospheric CO(2)
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title_full_unstemmed | Electroreductive Cobalt‐Catalyzed Carboxylation: Cross‐Electrophile Electrocoupling with Atmospheric CO(2)
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title_short | Electroreductive Cobalt‐Catalyzed Carboxylation: Cross‐Electrophile Electrocoupling with Atmospheric CO(2)
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title_sort | electroreductive cobalt‐catalyzed carboxylation: cross‐electrophile electrocoupling with atmospheric co(2) |
topic | Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496797/ https://www.ncbi.nlm.nih.gov/pubmed/32329560 http://dx.doi.org/10.1002/anie.202003218 |
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