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Cognitive function has a stronger correlation with perceived age than with chronological age
AIM: The perceived age of older adults, as measured by their facial appearance, has been shown to be a robust biomarker of aging predictive of survival, telomere length and DNA methylation, and reportedly correlates with carotid atherosclerosis and bone status. This study aimed to determine whether...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496800/ https://www.ncbi.nlm.nih.gov/pubmed/32618098 http://dx.doi.org/10.1111/ggi.13972 |
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author | Umeda‐Kameyama, Yumi Kameyama, Masashi Kojima, Taro Ishii, Masaki Kidana, Kiwami Yakabe, Mitsutaka Ishii, Shinya Urano, Tomohiko Ogawa, Sumito Akishita, Masahiro |
author_facet | Umeda‐Kameyama, Yumi Kameyama, Masashi Kojima, Taro Ishii, Masaki Kidana, Kiwami Yakabe, Mitsutaka Ishii, Shinya Urano, Tomohiko Ogawa, Sumito Akishita, Masahiro |
author_sort | Umeda‐Kameyama, Yumi |
collection | PubMed |
description | AIM: The perceived age of older adults, as measured by their facial appearance, has been shown to be a robust biomarker of aging predictive of survival, telomere length and DNA methylation, and reportedly correlates with carotid atherosclerosis and bone status. This study aimed to determine whether metrics of dementia, including general cognition, vitality, depressive state and self‐supportability, have stronger correlations with perceived age than with chronological age. METHODS: This study included 124 patients who were admitted to the Department of Geriatric Medicine, The University of Tokyo Hospital, on account of being suspected of cognitive decline. The Mini‐Mental State Examination, Vitality Index, Geriatric Depression Scale‐15, instrumental activities of daily living and Barthel Index were carried out. Five experienced geriatricians and five experienced clinical psychologists determined the perceived age of participants based on photographs. RESULTS: The average values of the 10 raters showed excellent reliability (intraclass correlation coefficient (3, 10) = 0.941). Steiger's test revealed that perceived age showed a significantly better correlation with the Mini‐Mental State Examination (female) and Vitality Index (total, female) than did chronological age, but not with Geriatric Depression Scale‐15, instrumental activities of daily living or the Barthel Index. CONCLUSIONS: Perceived age was shown to be a reliable biomarker for cognitive assessment. Geriatr Gerontol Int 2020; 20: 779–784. |
format | Online Article Text |
id | pubmed-7496800 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley & Sons Australia, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-74968002020-09-25 Cognitive function has a stronger correlation with perceived age than with chronological age Umeda‐Kameyama, Yumi Kameyama, Masashi Kojima, Taro Ishii, Masaki Kidana, Kiwami Yakabe, Mitsutaka Ishii, Shinya Urano, Tomohiko Ogawa, Sumito Akishita, Masahiro Geriatr Gerontol Int Original Articles: Epidemiology, Clinical Practice and Health AIM: The perceived age of older adults, as measured by their facial appearance, has been shown to be a robust biomarker of aging predictive of survival, telomere length and DNA methylation, and reportedly correlates with carotid atherosclerosis and bone status. This study aimed to determine whether metrics of dementia, including general cognition, vitality, depressive state and self‐supportability, have stronger correlations with perceived age than with chronological age. METHODS: This study included 124 patients who were admitted to the Department of Geriatric Medicine, The University of Tokyo Hospital, on account of being suspected of cognitive decline. The Mini‐Mental State Examination, Vitality Index, Geriatric Depression Scale‐15, instrumental activities of daily living and Barthel Index were carried out. Five experienced geriatricians and five experienced clinical psychologists determined the perceived age of participants based on photographs. RESULTS: The average values of the 10 raters showed excellent reliability (intraclass correlation coefficient (3, 10) = 0.941). Steiger's test revealed that perceived age showed a significantly better correlation with the Mini‐Mental State Examination (female) and Vitality Index (total, female) than did chronological age, but not with Geriatric Depression Scale‐15, instrumental activities of daily living or the Barthel Index. CONCLUSIONS: Perceived age was shown to be a reliable biomarker for cognitive assessment. Geriatr Gerontol Int 2020; 20: 779–784. John Wiley & Sons Australia, Ltd 2020-07-02 2020-08 /pmc/articles/PMC7496800/ /pubmed/32618098 http://dx.doi.org/10.1111/ggi.13972 Text en © 2020 The Authors. Geriatrics & Gerontology International published by John Wiley & Sons Australia, Ltd on behalf of Japan Geriatrics Society This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles: Epidemiology, Clinical Practice and Health Umeda‐Kameyama, Yumi Kameyama, Masashi Kojima, Taro Ishii, Masaki Kidana, Kiwami Yakabe, Mitsutaka Ishii, Shinya Urano, Tomohiko Ogawa, Sumito Akishita, Masahiro Cognitive function has a stronger correlation with perceived age than with chronological age |
title | Cognitive function has a stronger correlation with perceived age than with chronological age |
title_full | Cognitive function has a stronger correlation with perceived age than with chronological age |
title_fullStr | Cognitive function has a stronger correlation with perceived age than with chronological age |
title_full_unstemmed | Cognitive function has a stronger correlation with perceived age than with chronological age |
title_short | Cognitive function has a stronger correlation with perceived age than with chronological age |
title_sort | cognitive function has a stronger correlation with perceived age than with chronological age |
topic | Original Articles: Epidemiology, Clinical Practice and Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496800/ https://www.ncbi.nlm.nih.gov/pubmed/32618098 http://dx.doi.org/10.1111/ggi.13972 |
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