Structure‐Activity Relationship of Phenylpyrazolones against Trypanosoma cruzi

Chagas disease is a neglected parasitic disease caused by the parasitic protozoan Trypanosoma cruzi and currently affects around 8 million people. Previously, 2‐isopropyl‐5‐(4‐methoxy‐3‐(pyridin‐3‐yl)phenyl)‐4,4‐dimethyl‐2,4‐dihydro‐3H‐pyrazol‐3‐one (NPD‐0227) was discovered to be a sub‐micromolar i...

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Detalles Bibliográficos
Autores principales: Sijm, Maarten, Sterk, Geert Jan, Caljon, Guy, Maes, Louis, de Esch, Iwan J. P., Leurs, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496920/
https://www.ncbi.nlm.nih.gov/pubmed/32249532
http://dx.doi.org/10.1002/cmdc.202000136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496920/
https://www.ncbi.nlm.nih.gov/pubmed/32249532
http://dx.doi.org/10.1002/cmdc.202000136

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