Cargando…
Large‐Scale Production of LGR5‐Positive Bipotential Human Liver Stem Cells
BACKGROUND AND AIMS: The gap between patients on transplant waiting lists and available donor organs is steadily increasing. Human organoids derived from leucine‐rich repeat‐containing G protein‐coupled receptor 5 (LGR5)–positive adult stem cells represent an exciting new cell source for liver regen...
Autores principales: | Schneeberger, Kerstin, Sánchez‐Romero, Natalia, Ye, Shicheng, van Steenbeek, Frank G., Oosterhoff, Loes A., Pla Palacin, Iris, Chen, Chen, van Wolferen, Monique E., van Tienderen, Gilles, Lieshout, Ruby, Colemonts‐Vroninks, Haaike, Schene, Imre, Hoekstra, Ruurdtje, Verstegen, Monique M.A., van der Laan, Luc J.W., Penning, Louis C., Fuchs, Sabine A., Clevers, Hans, De Kock, Joery, Baptista, Pedro M., Spee, Bart |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496924/ https://www.ncbi.nlm.nih.gov/pubmed/31715015 http://dx.doi.org/10.1002/hep.31037 |
Ejemplares similares
-
Hepatocyte‐like cells generated by direct reprogramming from murine somatic cells can repopulate decellularized livers
por: Chen, Chen, et al.
Publicado: (2018) -
A Chemically Defined Hydrogel for Human Liver Organoid Culture
por: Ye, Shicheng, et al.
Publicado: (2020) -
Oxidative Stress, Glutathione Metabolism, and Liver Regeneration Pathways Are Activated in Hereditary Tyrosinemia Type 1 Mice upon Short-Term Nitisinone Discontinuation
por: Colemonts-Vroninks, Haaike, et al.
Publicado: (2020) -
Characterization and Comparison of Canine Multipotent Stromal Cells Derived from Liver and Bone Marrow
por: Malagola, Ermanno, et al.
Publicado: (2016) -
Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways
por: Haaike, Colemonts-Vroninks, et al.
Publicado: (2022)