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DNA Nanostructures for Targeted Antimicrobial Delivery

We report the use of DNA origami nanostructures, functionalized with aptamers, as a vehicle for delivering the antibacterial enzyme lysozyme in a specific and efficient manner. We test the system against Gram‐positive (Bacillus subtilis) and Gram‐negative (Escherichia coli) targets. We use direct st...

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Detalles Bibliográficos
Autores principales:	Mela, Ioanna, Vallejo‐Ramirez, Pedro P., Makarchuk, Stanislaw, Christie, Graham, Bailey, David, Henderson, Robert M., Sugiyama, Hiroshi, Endo, Masayuki, Kaminski, Clemens F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496991/ https://www.ncbi.nlm.nih.gov/pubmed/32297692 http://dx.doi.org/10.1002/anie.202002740

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