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Therapeutic modulation of inflammasome pathways

Inflammasomes are macromolecular complexes formed in response to pathogen‐associated molecular patterns (PAMPs) and danger‐associated molecular patterns (DAMPs) that drive maturation of the pro‐inflammatory cytokines interleukin (IL)‐1β and IL‐18, and cleave gasdermin D (GSDMD) for induction of pyro...

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Detalles Bibliográficos
Autores principales: Chauhan, Dhruv, Vande Walle, Lieselotte, Lamkanfi, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497261/
https://www.ncbi.nlm.nih.gov/pubmed/32770571
http://dx.doi.org/10.1111/imr.12908

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