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2′/3′ Regioselectivity of Enzyme‐Free Copying of RNA Detected by NMR

The RNA‐templated extension of oligoribonucleotides by nucleotides produces either a 3′,5′ or a 2′,5′‐phosphodiester. Nature controls the regioselectivity during RNA chain growth with polymerases, but enzyme‐free versions of genetic copying have modest specificity. Thus far, enzymatic degradation of...

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Detalles Bibliográficos
Autores principales: Motsch, Sebastian, Pfeffer, Daniel, Richert, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497262/
https://www.ncbi.nlm.nih.gov/pubmed/32017335
http://dx.doi.org/10.1002/cbic.202000014

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