Protection of Sacubitril/Valsartan against Pathological Cardiac Remodeling by Inhibiting the NLRP3 Inflammasome after Relief of Pressure Overload in Mice

BACKGROUND/AIMS: The persistent existence of pathological cardiac remodeling, resulting from aortic stenosis, is related to poor clinical prognosis after successful transcatheter aortic valve replacement (TAVR). Sacubitril/valsartan (Sac/Val), comprising an angiotensin receptor blocker and a neprily...

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Detalles Bibliográficos
Autores principales: Li, Xueling, Zhu, Qin, Wang, Qingcheng, Zhang, Qinggang, Zheng, Yaru, Wang, Lihong, Jin, Qinyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497317/
https://www.ncbi.nlm.nih.gov/pubmed/32444995
http://dx.doi.org/10.1007/s10557-020-06995-x

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