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[(18)F]AZD2461, an Insight on Difference in PARP Binding Profiles for DNA Damage Response PET Imaging

BACKGROUND: Poly (ADP-ribose) polymerase (PARP) inhibitors are extensively studied and used as anti-cancer drugs, as single agents or in combination with other therapies. Most radiotracers developed to date have been chosen on the basis of strong PARP1–3 affinity. Herein, we propose to study AZD2461...

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Detalles Bibliográficos
Autores principales:	Guibbal, Florian, Hopkins, Samantha L., Pacelli, Anna, Isenegger, Patrick G., Mosley, Michael, Torres, Julia Baguña, Dias, Gemma M., Mahaut, Damien, Hueting, Rebekka, Gouverneur, Véronique, Cornelissen, Bart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497465/ https://www.ncbi.nlm.nih.gov/pubmed/32342268 http://dx.doi.org/10.1007/s11307-020-01497-6

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