Cargando…

Long-term sequelae secondary to snakebite envenoming: a single centre retrospective study in a Costa Rican paediatric hospital

OBJECTIVES: Although devastating acute effects associated with snake envenoming are well described, the long-term sequelae resulting from these envenomings have not been adequately addressed, especially in the paediatric population. The aim of our study is to describe the clinical characteristics am...

Descripción completa

Detalles Bibliográficos
Autores principales: Brenes-Chacon, Helena, Gutierrez, Jose M, Camacho-Badilla, Kattia, Soriano-Fallas, Alejandra, Ulloa-Gutierrez, Rolando, Valverde, Kattia, Avila-Aguero, María Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497519/
https://www.ncbi.nlm.nih.gov/pubmed/32995568
http://dx.doi.org/10.1136/bmjpo-2020-000735
_version_ 1783583334097485824
author Brenes-Chacon, Helena
Gutierrez, Jose M
Camacho-Badilla, Kattia
Soriano-Fallas, Alejandra
Ulloa-Gutierrez, Rolando
Valverde, Kattia
Avila-Aguero, María Luisa
author_facet Brenes-Chacon, Helena
Gutierrez, Jose M
Camacho-Badilla, Kattia
Soriano-Fallas, Alejandra
Ulloa-Gutierrez, Rolando
Valverde, Kattia
Avila-Aguero, María Luisa
author_sort Brenes-Chacon, Helena
collection PubMed
description OBJECTIVES: Although devastating acute effects associated with snake envenoming are well described, the long-term sequelae resulting from these envenomings have not been adequately addressed, especially in the paediatric population. The aim of our study is to describe the clinical characteristics among paediatric patients in Costa Rica who developed long-term sequelae secondary to snakebite envenoming. DESIGN: Retrospective descriptive study of paediatric patients under 13 years who were admitted with a history of a recent snakebite at the National Children’s Hospital in Costa Rica from January 2001 to December 2014. RESULTS: We enrolled 74 patients admitted to our centre due to envenoming, and separated those who did not develop sequelae (50 patients) from those who did (24 patients). Of those who presented acute complications during hospitalisation, local wound infection and clinically diagnosed compartmental syndrome were significantly higher in the group that developed sequelae thereafter. Hypertrophic scars (66.7%), functional limitation of affected limb (37.5%) and the need of skin graft (37.5%) were the most common sequelae. The median follow-up of patients with long-term sequelae after discharge was 25.4 months (5.6–59.4). No deaths were reported during this time period. CONCLUSIONS: Given the high economic, personal and healthcare burden that entails follow-up of these patients, efforts should be carried out to prevent the factors associated with sequelae among the affected population.
format Online
Article
Text
id pubmed-7497519
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-74975192020-09-28 Long-term sequelae secondary to snakebite envenoming: a single centre retrospective study in a Costa Rican paediatric hospital Brenes-Chacon, Helena Gutierrez, Jose M Camacho-Badilla, Kattia Soriano-Fallas, Alejandra Ulloa-Gutierrez, Rolando Valverde, Kattia Avila-Aguero, María Luisa BMJ Paediatr Open Infectious Diseases OBJECTIVES: Although devastating acute effects associated with snake envenoming are well described, the long-term sequelae resulting from these envenomings have not been adequately addressed, especially in the paediatric population. The aim of our study is to describe the clinical characteristics among paediatric patients in Costa Rica who developed long-term sequelae secondary to snakebite envenoming. DESIGN: Retrospective descriptive study of paediatric patients under 13 years who were admitted with a history of a recent snakebite at the National Children’s Hospital in Costa Rica from January 2001 to December 2014. RESULTS: We enrolled 74 patients admitted to our centre due to envenoming, and separated those who did not develop sequelae (50 patients) from those who did (24 patients). Of those who presented acute complications during hospitalisation, local wound infection and clinically diagnosed compartmental syndrome were significantly higher in the group that developed sequelae thereafter. Hypertrophic scars (66.7%), functional limitation of affected limb (37.5%) and the need of skin graft (37.5%) were the most common sequelae. The median follow-up of patients with long-term sequelae after discharge was 25.4 months (5.6–59.4). No deaths were reported during this time period. CONCLUSIONS: Given the high economic, personal and healthcare burden that entails follow-up of these patients, efforts should be carried out to prevent the factors associated with sequelae among the affected population. BMJ Publishing Group 2020-09-16 /pmc/articles/PMC7497519/ /pubmed/32995568 http://dx.doi.org/10.1136/bmjpo-2020-000735 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Infectious Diseases
Brenes-Chacon, Helena
Gutierrez, Jose M
Camacho-Badilla, Kattia
Soriano-Fallas, Alejandra
Ulloa-Gutierrez, Rolando
Valverde, Kattia
Avila-Aguero, María Luisa
Long-term sequelae secondary to snakebite envenoming: a single centre retrospective study in a Costa Rican paediatric hospital
title Long-term sequelae secondary to snakebite envenoming: a single centre retrospective study in a Costa Rican paediatric hospital
title_full Long-term sequelae secondary to snakebite envenoming: a single centre retrospective study in a Costa Rican paediatric hospital
title_fullStr Long-term sequelae secondary to snakebite envenoming: a single centre retrospective study in a Costa Rican paediatric hospital
title_full_unstemmed Long-term sequelae secondary to snakebite envenoming: a single centre retrospective study in a Costa Rican paediatric hospital
title_short Long-term sequelae secondary to snakebite envenoming: a single centre retrospective study in a Costa Rican paediatric hospital
title_sort long-term sequelae secondary to snakebite envenoming: a single centre retrospective study in a costa rican paediatric hospital
topic Infectious Diseases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497519/
https://www.ncbi.nlm.nih.gov/pubmed/32995568
http://dx.doi.org/10.1136/bmjpo-2020-000735
work_keys_str_mv AT breneschaconhelena longtermsequelaesecondarytosnakebiteenvenomingasinglecentreretrospectivestudyinacostaricanpaediatrichospital
AT gutierrezjosem longtermsequelaesecondarytosnakebiteenvenomingasinglecentreretrospectivestudyinacostaricanpaediatrichospital
AT camachobadillakattia longtermsequelaesecondarytosnakebiteenvenomingasinglecentreretrospectivestudyinacostaricanpaediatrichospital
AT sorianofallasalejandra longtermsequelaesecondarytosnakebiteenvenomingasinglecentreretrospectivestudyinacostaricanpaediatrichospital
AT ulloagutierrezrolando longtermsequelaesecondarytosnakebiteenvenomingasinglecentreretrospectivestudyinacostaricanpaediatrichospital
AT valverdekattia longtermsequelaesecondarytosnakebiteenvenomingasinglecentreretrospectivestudyinacostaricanpaediatrichospital
AT avilaagueromarialuisa longtermsequelaesecondarytosnakebiteenvenomingasinglecentreretrospectivestudyinacostaricanpaediatrichospital