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Longitudinal associations between loneliness, social isolation and cardiovascular events
OBJECTIVE: This study aimed to examine the association between loneliness, social isolation and cardiovascular disease (CVD), looking at both self-reported CVD diagnosis and CVD-related hospital admissions. METHODS: Data were derived from the English Longitudinal Study of Ageing linked with administ...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497558/ https://www.ncbi.nlm.nih.gov/pubmed/32461329 http://dx.doi.org/10.1136/heartjnl-2020-316614 |
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author | Bu, Feifei Zaninotto, Paola Fancourt, Daisy |
author_facet | Bu, Feifei Zaninotto, Paola Fancourt, Daisy |
author_sort | Bu, Feifei |
collection | PubMed |
description | OBJECTIVE: This study aimed to examine the association between loneliness, social isolation and cardiovascular disease (CVD), looking at both self-reported CVD diagnosis and CVD-related hospital admissions. METHODS: Data were derived from the English Longitudinal Study of Ageing linked with administrative hospital records and mortality registry data. The analytical sample size was 5850 for the analysis of self-reported CVD and 4587 of CVD derived from hospital records, with a follow-up up to 9.6 years. Data were analysed using survival analysis, accounting for competing risks events. RESULTS: The mean age was 64 years (SD 8.3). About 44%–45% were men. Within the follow-up, 17% participants reported having newly diagnosed CVD and 16% had a CVD-related hospital admission. We found that loneliness was associated with an increased risk of CVD events independent of potential confounders and risk factors. The hazard of people with the highest level of loneliness was about 30% higher for onset CVD diagnosis (HR: 1.05, 95% CI: 1.01 to 1.09) and 48% higher for CVD-related hospital admissions (HR: 1.08, 95% CI: 1.03 to 1.14), compared with the least lonely. There was little evidence that social isolation was independently associated with the risk of either CVD diagnosis or admission. CONCLUSIONS: Our findings provided strong evidence for the relationship between loneliness and cardiovascular events. Loneliness should be considered as a psychosocial risk factor for CVD in both research and interventions for cardiovascular prevention. |
format | Online Article Text |
id | pubmed-7497558 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-74975582020-09-28 Longitudinal associations between loneliness, social isolation and cardiovascular events Bu, Feifei Zaninotto, Paola Fancourt, Daisy Heart Cardiac Risk Factors and Prevention OBJECTIVE: This study aimed to examine the association between loneliness, social isolation and cardiovascular disease (CVD), looking at both self-reported CVD diagnosis and CVD-related hospital admissions. METHODS: Data were derived from the English Longitudinal Study of Ageing linked with administrative hospital records and mortality registry data. The analytical sample size was 5850 for the analysis of self-reported CVD and 4587 of CVD derived from hospital records, with a follow-up up to 9.6 years. Data were analysed using survival analysis, accounting for competing risks events. RESULTS: The mean age was 64 years (SD 8.3). About 44%–45% were men. Within the follow-up, 17% participants reported having newly diagnosed CVD and 16% had a CVD-related hospital admission. We found that loneliness was associated with an increased risk of CVD events independent of potential confounders and risk factors. The hazard of people with the highest level of loneliness was about 30% higher for onset CVD diagnosis (HR: 1.05, 95% CI: 1.01 to 1.09) and 48% higher for CVD-related hospital admissions (HR: 1.08, 95% CI: 1.03 to 1.14), compared with the least lonely. There was little evidence that social isolation was independently associated with the risk of either CVD diagnosis or admission. CONCLUSIONS: Our findings provided strong evidence for the relationship between loneliness and cardiovascular events. Loneliness should be considered as a psychosocial risk factor for CVD in both research and interventions for cardiovascular prevention. BMJ Publishing Group 2020-09 2020-05-27 /pmc/articles/PMC7497558/ /pubmed/32461329 http://dx.doi.org/10.1136/heartjnl-2020-316614 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/ https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Cardiac Risk Factors and Prevention Bu, Feifei Zaninotto, Paola Fancourt, Daisy Longitudinal associations between loneliness, social isolation and cardiovascular events |
title | Longitudinal associations between loneliness, social isolation and cardiovascular events |
title_full | Longitudinal associations between loneliness, social isolation and cardiovascular events |
title_fullStr | Longitudinal associations between loneliness, social isolation and cardiovascular events |
title_full_unstemmed | Longitudinal associations between loneliness, social isolation and cardiovascular events |
title_short | Longitudinal associations between loneliness, social isolation and cardiovascular events |
title_sort | longitudinal associations between loneliness, social isolation and cardiovascular events |
topic | Cardiac Risk Factors and Prevention |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497558/ https://www.ncbi.nlm.nih.gov/pubmed/32461329 http://dx.doi.org/10.1136/heartjnl-2020-316614 |
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