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Synthesis of Trifluoromethylated Purine Ribonucleotides and Their Evaluation as (19)F NMR Probes

[Image: see text] Protected guanosine and adenosine ribonucleosides and guanine nucleotides are readily functionalized with CF(3) substituents within the nucleobase. Protected guanosine is trifluoromethylated at the C8 position under radical-generating conditions in up to 95% yield and guanosine 5′-...

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Detalles Bibliográficos
Autores principales:	Chrominski, Mikolaj, Baranowski, Marek R., Chmielinski, Sebastian, Kowalska, Joanna, Jemielity, Jacek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497640/ https://www.ncbi.nlm.nih.gov/pubmed/31994393 http://dx.doi.org/10.1021/acs.joc.9b03198

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