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Administration of the vasopressin analog desmopressin for the management of bleeding in rectal cancer patients: results of a phase I/II trial

Purpose The vasopressin analog desmopressin (dDAVP) is known to increase plasma levels of hemostatic factors, and preclinical studies in colorectal cancer models have demonstrated that it hampers tumor vascularization and metastatic progression. We evaluated safety and preliminary efficacy of dDAVP...

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Detalles Bibliográficos
Autores principales: Iseas, Soledad, Roca, Enrique L., O’Connor, Juan M., Eleta, Martin, Sanchez-Luceros, Analia, Di Leo, Daniela, Tinelli, Marcelo, Fara, Maria L., Spitzer, Eduardo, Demarco, Ignacio A., Ripoll, Giselle V., Pifano, Marina, Garona, Juan, Alonso, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497699/
https://www.ncbi.nlm.nih.gov/pubmed/32166534
http://dx.doi.org/10.1007/s10637-020-00914-5