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Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds

[Image: see text] The mechanical properties of scaffolds used for mechanically challenging applications such as cardiovascular implants are unequivocally important. Here, the effect of supramolecular additive functionalization on mechanical behavior of electrospun scaffolds was investigated for one...

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Autores principales: Ippel, Bastiaan D., Van Haaften, Eline E., Bouten, Carlijn V. C., Dankers, Patricia Y. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497720/
https://www.ncbi.nlm.nih.gov/pubmed/32954355
http://dx.doi.org/10.1021/acsapm.0c00658
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author Ippel, Bastiaan D.
Van Haaften, Eline E.
Bouten, Carlijn V. C.
Dankers, Patricia Y. W.
author_facet Ippel, Bastiaan D.
Van Haaften, Eline E.
Bouten, Carlijn V. C.
Dankers, Patricia Y. W.
author_sort Ippel, Bastiaan D.
collection PubMed
description [Image: see text] The mechanical properties of scaffolds used for mechanically challenging applications such as cardiovascular implants are unequivocally important. Here, the effect of supramolecular additive functionalization on mechanical behavior of electrospun scaffolds was investigated for one bisurea-based model additive and two previously developed antifouling additives. The model additive has no effect on the mechanical properties of the bulk material, whereas the stiffness of electrospun scaffolds was slightly decreased compared to pristine PCL-BU following the addition of the three different additives. These results show the robustness of supramolecular additives used in biomedical applications, in which mechanical properties are important, such as vascular grafts and heart valve constructs.
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spelling pubmed-74977202020-09-18 Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds Ippel, Bastiaan D. Van Haaften, Eline E. Bouten, Carlijn V. C. Dankers, Patricia Y. W. ACS Appl Polym Mater [Image: see text] The mechanical properties of scaffolds used for mechanically challenging applications such as cardiovascular implants are unequivocally important. Here, the effect of supramolecular additive functionalization on mechanical behavior of electrospun scaffolds was investigated for one bisurea-based model additive and two previously developed antifouling additives. The model additive has no effect on the mechanical properties of the bulk material, whereas the stiffness of electrospun scaffolds was slightly decreased compared to pristine PCL-BU following the addition of the three different additives. These results show the robustness of supramolecular additives used in biomedical applications, in which mechanical properties are important, such as vascular grafts and heart valve constructs. American Chemical Society 2020-08-18 2020-09-11 /pmc/articles/PMC7497720/ /pubmed/32954355 http://dx.doi.org/10.1021/acsapm.0c00658 Text en Copyright © 2020 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.
spellingShingle Ippel, Bastiaan D.
Van Haaften, Eline E.
Bouten, Carlijn V. C.
Dankers, Patricia Y. W.
Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds
title Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds
title_full Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds
title_fullStr Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds
title_full_unstemmed Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds
title_short Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds
title_sort impact of additives on mechanical properties of supramolecular electrospun scaffolds
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497720/
https://www.ncbi.nlm.nih.gov/pubmed/32954355
http://dx.doi.org/10.1021/acsapm.0c00658
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