Cargando…
Cdk1 Phosphorylation of the Dam1 Complex Strengthens Kinetochore-Microtubule Attachments
To ensure the faithful inheritance of DNA, a macromolecular protein complex called the kinetochore sustains the connection between chromosomes and force-generating dynamic microtubules during cell division. Defects in this process lead to aneuploidy, a common feature of cancer cells and the cause of...
Autores principales: | Gutierrez, Abraham, Kim, Jae ook, Umbreit, Neil T., Asbury, Charles L., Davis, Trisha N., Miller, Matthew P., Biggins, Sue |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497780/ https://www.ncbi.nlm.nih.gov/pubmed/32946748 http://dx.doi.org/10.1016/j.cub.2020.08.054 |
Ejemplares similares
-
Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation
por: Umbreit, Neil T., et al.
Publicado: (2014) -
Kinetochore-bound Mps1 regulates kinetochore–microtubule attachments via Ndc80 phosphorylation
por: Sarangapani, Krishna K., et al.
Publicado: (2021) -
Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B
por: Tien, Jerry F., et al.
Publicado: (2010) -
DASH/Dam1 complex mutants stabilize ploidy in histone‐humanized yeast by weakening kinetochore‐microtubule attachments
por: Haase, Max A B, et al.
Publicado: (2023) -
Tension can directly suppress Aurora B kinase-triggered release of kinetochore-microtubule attachments
por: de Regt, Anna K., et al.
Publicado: (2022)