Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model

The glycome undergoes characteristic changes during histogenesis and organogenesis, but our understanding of the importance of select glycan structures for tissue formation and homeostasis is incomplete. Here, we present a human organotypic platform that allows genetic dissection of cellular glycosy...

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Detalles Bibliográficos
Autores principales: Dabelsteen, Sally, Pallesen, Emil M.H., Marinova, Irina N., Nielsen, Mathias I., Adamopoulou, Maria, Rømer, Troels B., Levann, Asha, Andersen, Mikkel M., Ye, Zilu, Thein, David, Bennett, Eric P., Büll, Christian, Moons, Sam J., Boltje, Thomas, Clausen, Henrik, Vakhrushev, Sergey Y., Bagdonaite, Ieva, Wandall, Hans H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497784/
https://www.ncbi.nlm.nih.gov/pubmed/32710848
http://dx.doi.org/10.1016/j.devcel.2020.06.039

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