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Pancreatic Steatosis Associates With Impaired Insulin Secretion in Genetically Predisposed Individuals
CONTEXT: Pancreatic steatosis leading to beta-cell failure might be involved in type 2 diabetes (T2D) pathogenesis. OBJECTIVE: We hypothesized that the genetic background modulates the effect of pancreatic fat on beta-cell function and investigated genotype × pancreatic fat interactions on insulin s...
Autores principales: | Wagner, Róbert, Jaghutriz, Benjamin Assad, Gerst, Felicia, Barroso Oquendo, Morgana, Machann, Jürgen, Schick, Fritz, Löffler, Markus W, Nadalin, Silvio, Fend, Falko, Königsrainer, Alfred, Peter, Andreas, Siegel-Axel, Dorothea, Ullrich, Susanne, Häring, Hans-Ulrich, Fritsche, Andreas, Heni, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497818/ https://www.ncbi.nlm.nih.gov/pubmed/32725157 http://dx.doi.org/10.1210/clinem/dgaa435 |
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